This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBabe puro C-Raf 22W
catalog :
12593
citations: 5
Reference
Pomeroy E, Lee L, Lee R, Schirm D, Temiz N, Ma J, et al. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017;36:3263-3273 pubmed publisher
Mattison S, Blatch G, Edkins A. HOP expression is regulated by p53 and RAS and characteristic of a cancer gene signature. Cell Stress Chaperones. 2017;22:213-223 pubmed publisher
Wang C, Qin L, Manes T, Kirkiles Smith N, Tellides G, Pober J. Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2. J Exp Med. 2014;211:395-404 pubmed publisher
Cipriano R, Miskimen K, Bryson B, Foy C, Bartel C, Jackson M. FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Oncotarget. 2013;4:729-38 pubmed
McFall A, Ulku A, Lambert Q, Kusa A, Rogers Graham K, Der C. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase. Mol Cell Biol. 2001;21:5488-99 pubmed
product information
Catalog Number :
12593
Product Name :
pBabe puro C-Raf 22W
article :
doi10.1128/MCB.21.16.5488-5499.2001
id928
pubmed_id11463831
bacterial resistance :
Ampicillin
cloning :
backbonepBabe puro
backbone_mutation
backbone_origin
backbone_size5169
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
c-Raf 22W
Raf
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3pBabe 3'
sequencing_primer_5pBabe 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCMD1NN, CRAF, NS5, Raf-1, c-Raf
geneRAF1
id5894
genbank_ids
mutation22W, N-terminally truncated
nameN-term truncated mut of Raf-1
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
114
tags :
Unknown
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA