This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pD21-AI-hLDLR
catalog :
124964
citations: 1
Reference
Li R, Chao H, Ko K, Cormier S, Dieker C, Nour E, et al. Gene Therapy Targeting LDL Cholesterol but not HDL Cholesterol Induces Regression of Advanced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia. J Genet Syndr Gene Ther. 2011;2:106 pubmed
product information
Catalog Number :
124964
Product Name :
pD21-AI-hLDLR
article :
doi10.4172/2157-7412.1000106
id28197685
pubmed_id23106034
bacterial resistance :
Ampicillin
cloning :
backbonepD21
backbone_mutation
backbone_originBCM
backbone_size24000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Adenoviral
growth notes :
As this plasmid is very large, NGS had difficulty sequencing it. There are several differences between Addgene's NGS and depositors sequence. We recommend running additional diagnostic tests before use. Depositor also recommends growing plasmid at 30 degrees C due to their size.
growth strain :
Express human LDLR under human APOAI promoter
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5Unknown
promoterhuman APOAI
sequencing_primer_3
sequencing_primer_5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesFH, FHC, FHCL1, LDLCQ2
geneLDLR
id3949
genbank_ids
mutation
namehuman LDLR
shRNA_sequence
size
species
9606
Homo sapiens
tags
resistance markers :
2685
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA