This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pKT-IDH1(R132H)-IRES-Katushka
catalog :
124257
citations: 1
Reference
Nunez F, Mendez F, Kadiyala P, Alghamri M, Savelieff M, Garcia Fabiani M, et al. IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response. Sci Transl Med. 2019;11: pubmed publisher
product information
Catalog Number :
124257
Product Name :
pKT-IDH1(R132H)-IRES-Katushka
article :
doi10.1126/scitranslmed.aaq1427
id28197541
pubmed_id30760578
bacterial resistance :
Kanamycin
cloning :
backbonepKT
backbone_mutation
backbone_origin
backbone_size4891
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses IDH1 with a R132H mutation and katushka fluorescent reporter. Construct has inverted repeats to be used in Sleeping Beauty transposon system.
origin :
37
pi :
alt_names
IDH1 (R132H)
cloning
entrez_gene
aliasesHEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD
geneIDH1
id3417
genbank_ids
mutationArginine 132 is mutated to Histidine. This mutation is found in Low Grade Gliomas and produces the oncometabolite, 2-Hydroxyglutarate.
nameIsocitrate dehydrogenase 1 (R132H)
shRNA_sequence
size1258
species
9606
Homo sapiens
tags
resistance markers :
70
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA