This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pAJ075_hsCRBN
catalog :
124214
citations: 2
Reference
Nie X, Zhao Y, Tang H, Zhang Z, Liao J, Almodovar Rivera C, et al. Development of Phenyl-substituted Isoindolinone- and Benzimidazole-type Cereblon Ligands for Targeted Protein Degradation. Chembiochem. 2023;:e202300685 pubmed publisher
Nowak R, DeAngelo S, Buckley D, He Z, Donovan K, An J, et al. Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat Chem Biol. 2018;14:706-714 pubmed publisher
product information
Catalog Number :
124214
Product Name :
pAJ075_hsCRBN
article :
doi10.1038/s41589-018-0055-y
id28197526
pubmed_id29892083
bacterial resistance :
Ampicillin
cloning :
backbonepAC8
backbone_mutation
backbone_originn/a
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Insect Expression
growth strain :
Insect cell expression vector for His6 tagged hsCRBN
origin :
37
pi :
alt_names
CRBN
cloning
entrez_gene
aliasesMRT2, MRT2A
geneCRBN
id51185
genbank_ids
mutation
nameCereblon
shRNA_sequence
size1326
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHis6-TEV
resistance markers :
4383
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA