This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pIRES2-EGFP-SHP2DA
catalog :
12286
citations: 3
Reference
Rhoads S, Monahan Z, Yee D, Leung A, Newcombe C, O Meally R, et al. The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization. Mol Biol Cell. 2018;29:1786-1797 pubmed publisher
Wu N, Kurosu T, Oshikawa G, Nagao T, Miura O. PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells. Int J Oncol. 2013;42:419-28 pubmed publisher
Kolli S, Zito C, Mossink M, Wiemer E, Bennett A. The major vault protein is a novel substrate for the tyrosine phosphatase SHP-2 and scaffold protein in epidermal growth factor signaling. J Biol Chem. 2004;279:29374-85 pubmed
product information
Catalog Number :
12286
Product Name :
pIRES2-EGFP-SHP2DA
article :
doi10.1074/jbc.M313955200
id843
pubmed_id15133037
bacterial resistance :
Kanamycin
cloning :
backbonepIRES2-EGFP
backbone_mutation
backbone_originClontech
backbone_size3500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
PTP2C
PTP-1D
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
genePTPN11
id5781
genbank_ids
NP_002825
mutationAspartic Acid 425 mutated to Alanine
nameSHP-2DA
shRNA_sequence
size1900
species
9606
Homo sapiens
tags
locationC terminal on insert
tagMyc
plasmid copy :
Neel.BG Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA.
resistance markers :
26
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA