This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLKO.1 puro CXCR4 siRNA-1
catalog :
12271
citations: 4
Reference
Pan W, Wang Y, Hao Y, Wong J, Chan W, Wan D, et al. Overexpression of CXCR4 synergizes with LL-37 in the metastasis of breast cancer cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864:3837-3846 pubmed publisher
Wang Y, Liang W, Pan W, Law W, Hu J, Ip D, et al. Silibinin, a novel chemokine receptor type 4 antagonist, inhibits chemokine ligand 12-induced migration in breast cancer cells. Phytomedicine. 2014;21:1310-7 pubmed publisher
Krook M, Nicholls L, Scannell C, Chugh R, Thomas D, Lawlor E. Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. Mol Cancer Res. 2014;12:953-64 pubmed publisher
Orimo A, Gupta P, Sgroi D, Arenzana Seisdedos F, Delaunay T, Naeem R, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005;121:335-48 pubmed
product information
Catalog Number :
12271
Product Name :
pLKO.1 puro CXCR4 siRNA-1
article :
doi10.1016/j.cell.2005.02.034
id832
pubmed_id15882617
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1
backbone_mutation
backbone_origin
backbone_size7139
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth notes :
CXCR4-siRNA-1 sequence: 5'-TGGAGGGGATCAGTATATACA-3'
origin :
37
pi :
alt_names
CXCR4
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5AgeI
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, WHIMS1
geneCXCR4
id7852
genbank_ids
mutation
nameCXCR4 siRNA
shRNA_sequence
size59
species
9606
Homo sapiens
tags
resistance markers :
568
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA