This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Orai1
catalog :
12199
citations: 5
Reference
Wu T, Goriounova A, Worthington E, Wrennall J, Ghosh A, Ahmad S, et al. SPLUNC1 is a negative regulator of the Orai1 Ca2+ channel. Physiol Rep. 2022;10:e15306 pubmed publisher
Tsujikawa H, Yu A, Xie J, Yue Z, Yang W, He Y, et al. Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels. Sci Rep. 2015;5:16747 pubmed publisher
Saüc S, Bulla M, Nunes P, Orci L, Marchetti A, Antigny F, et al. STIM1L traps and gates Orai1 channels without remodeling the cortical ER. J Cell Sci. 2015;128:1568-79 pubmed publisher
Eltit J, Ding X, Pessah I, Allen P, Lopez J. Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia. FASEB J. 2013;27:991-1000 pubmed publisher
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel S, Tanasa B, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature. 2006;441:179-85 pubmed
product information
Catalog Number :
12199
Product Name :
Orai1
article :
doi10.1038/nature04702
id821
pubmed_id16582901
bacterial resistance :
Ampicillin
cloning :
backbonepMSCV-CITE-eGFP-PGK-Puro
backbone_mutation
backbone_originDr. Masatsugu Ohora
backbone_size7480
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5XhoI
promoter
sequencing_primer_3IRES-R
sequencing_primer_5na
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCRACM1, IMD9, ORAT1, TAM2, TMEM142A
geneORAI1
id84876
genbank_ids
mutation
nameOrai1
shRNA_sequence
size930
species
9606
Homo sapiens
tags
locationC terminal on insert
tagMyc
resistance markers :
410
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA