pCMV HDM2(C464A) | Addgene 12086 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pCMV HDM2(C464A)

catalog :

12086

citations: 3

Reference
Wohlberedt K, Klusmann I, Derevyanko P, Henningsen K, Choo J, Manzini V, et al. Mdm4 supports DNA replication in a p53-independent fashion. Oncogene. 2020;39:4828-4843 pubmed publisher
Schmidt M, Calvisi D, Clark G. NORE1A Regulates MDM2 Via ?-TrCP. Cancers (Basel). 2016;8: pubmed publisher
Boyd S, Tsai K, Jacks T. An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. Nat Cell Biol. 2000;2:563-8 pubmed

product information

Catalog Number :

12086

Product Name :

pCMV HDM2(C464A)

article :

doi	10.1038/35023500
id	723
pubmed_id	10980695

bacterial resistance :

Ampicillin

cloning :

backbone

pCMV5

backbone_mutation

backbone_origin

backbone_size

4600

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ACTFS, HDMX, LSKB, hdm2
gene	MDM2
id	4193

genbank_ids

mutation

C464A: RING-finger-domain mutant

name

HDM2

shRNA_sequence

size

species

9606

Homo sapiens