This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Xiap-Myc
catalog :
11833
citations: 10
Reference
Zhou H, Zeng H, Yuan D, Ren J, Cheng S, Yu H, et al. NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma. Cell Commun Signal. 2019;17:168 pubmed publisher
Kim J, Park S, Jeong S, Kim B, Na Y, Jo M, et al. Sea Cucumber (Stichopus japonicas) F2 Enhanced TRAIL-Induced Apoptosis via XIAP Ubiquitination and ER Stress in Colorectal Cancer Cells. Nutrients. 2019;11: pubmed publisher
Jacobs C, Badiee R, Lin M. StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins. Nat Methods. 2018;15:523-526 pubmed publisher
Liu X, Xu J, Li F, Li M, Hu T. Down-regulation of miR-377 contributes to cisplatin resistance by targeting XIAP in osteosarcoma. Eur Rev Med Pharmacol Sci. 2018;22:1249-1257 pubmed publisher
Ji J, Yu Y, Li Z, Chen M, Deng R, Huang X, et al. XIAP Limits Autophagic Degradation of Sox2 and Is A Therapeutic Target in Nasopharyngeal Carcinoma Stem Cells. Theranostics. 2018;8:1494-1510 pubmed publisher
Augeri D, Langenfeld E, Castle M, Gilleran J, Langenfeld J. Inhibition of BMP and of TGF? receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death. Mol Cancer. 2016;15:27 pubmed publisher
Lin F, Ghislat G, Luo S, Renna M, Siddiqi F, Rubinsztein D. XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation. Hum Mol Genet. 2015;24:2899-913 pubmed publisher
Winkler J, Ori A, Hölzer K, Sticht C, Dauch D, Eiteneuer E, et al. Prosurvival function of the cellular apoptosis susceptibility/importin-?1 transport cycle is repressed by p53 in liver cancer. Hepatology. 2014;60:884-95 pubmed publisher
Rajput S, Kumar B, Sarkar S, Das S, Azab B, Santhekadur P, et al. Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer. PLoS ONE. 2013;8:e61342 pubmed publisher
Ling X, Cao S, Cheng Q, Keefe J, Rustum Y, Li F. A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity. PLoS ONE. 2012;7:e45571 pubmed publisher
product information
Catalog Number :
11833
Product Name :
pcDNA3-Xiap-Myc
article :
doi
id673
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1
backbone_mutation
backbone_origin
backbone_size5428
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Don't Know
cloning_site_5Don't Know
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAPI3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
geneXIAP
id331
genbank_ids
mutation
nameXIAP
shRNA_sequence
size1600
species
9606
Homo sapiens
tags
locationN terminal on insert
tagMyc
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA