This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pET23b-Casp6-His
catalog :
11823
citations: 5
Reference
Zhou L, Nho K, Haddad M, Cherepacha N, Tubeleviciute Aydin A, Tsai A, et al. Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration. Sci Rep. 2021;11:12695 pubmed publisher
Tubeleviciute Aydin A, Zhou L, Sharma G, Soni I, Savinov S, Hardy J, et al. Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity. Sci Rep. 2018;8:4428 pubmed publisher
Weaver B, Weaver Y, Mitani S, Han M. Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Dev Cell. 2017;41:665-673.e6 pubmed publisher
Halawani D, Tessier S, Anzellotti D, Bennett D, Latterich M, LeBlanc A. Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation. J Neurosci. 2010;30:6132-42 pubmed publisher
Zhou Q, Snipas S, Orth K, Muzio M, Dixit V, Salvesen G. Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J Biol Chem. 1997;272:7797-800 pubmed
product information
Catalog Number :
11823
Product Name :
pET23b-Casp6-His
article :
doi10.1074/jbc.272.12.7797
id668
pubmed_id9065443
bacterial resistance :
Ampicillin
cloning :
backbonepET-23 b
backbone_mutation
backbone_origin
backbone_size3666
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NdeI
cloning_site_5XhoI
promoter
sequencing_primer_3
sequencing_primer_5T7 terminal primer
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCSP-6, MCH2, caspase-6
geneCASP6
id839
genbank_ids
mutation
nameCaspase 6
shRNA_sequence
size988
species
9606
Homo sapiens
tags
locationC terminal on insert
tag6xHis
resistance markers :
435
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA