This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Casp9 C287A
catalog :
11819
citations: 5
Reference
Booth L, West C, Von Hoff D, Kirkwood J, Dent P. GZ17-6.02 Interacts With [MEK1/2 and B-RAF Inhibitors] to Kill Melanoma Cells. Front Oncol. 2021;11:656453 pubmed publisher
Oladzad A, Nikkhah M, Hosseinkhani S. Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells. Sensors (Basel). 2020;20: pubmed publisher
Pesakhov S, Nachliely M, Barvish Z, Aqaqe N, Schwartzman B, Voronov E, et al. Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid. Oncotarget. 2016;7:31847-61 pubmed publisher
Boston S, Deshmukh R, Strome S, Priyakumar U, MacKerell A, Shapiro P. Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9. BMC Cancer. 2011;11:7 pubmed publisher
Stennicke H, Deveraux Q, Humke E, Reed J, Dixit V, Salvesen G. Caspase-9 can be activated without proteolytic processing. J Biol Chem. 1999;274:8359-62 pubmed
product information
Catalog Number :
11819
Product Name :
pcDNA3-Casp9 C287A
article :
doi10.1074/jbc.274.13.8359
id670
pubmed_id10085063
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Caspase 9
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5HindIII
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAPAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
geneCASP9
id842
genbank_ids
mutationC287A, catalytically incompetent mutant.
nameCaspase 9 catalytically incompetent mutant
shRNA_sequence
size1392
species
9606
Homo sapiens
tags
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA