This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Casp8 C360A
catalog :
11818
citations: 4
Reference
Bhatt T, Bhosale A, Bajantri B, Mathapathi M, Rizvi A, Scita G, et al. Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8. Cell Rep. 2019;29:2546-2555.e4 pubmed publisher
Pesakhov S, Nachliely M, Barvish Z, Aqaqe N, Schwartzman B, Voronov E, et al. Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid. Oncotarget. 2016;7:31847-61 pubmed publisher
Treude F, Kappes F, Fahrenkamp D, Muller Newen G, Dajas Bailador F, Kramer O, et al. Caspase-8-mediated PAR-4 cleavage is required for TNF?-induced apoptosis. Oncotarget. 2014;5:2988-98 pubmed
Stennicke H, Salvesen G. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem. 1997;272:25719-23 pubmed
product information
Catalog Number :
11818
Product Name :
pcDNA3-Casp8 C360A
article :
doi10.1074/jbc.272.41.25719
id671
pubmed_id9325297
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Caspase 8 isoform B
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
geneCASP8
id841
genbank_ids
mutationC360A
nameCaspase 8 catalytic mutant
shRNA_sequence
size1354
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHA
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA