This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Casp8
catalog :
11817
citations: 7
Reference
Nguyen T, Nagamune T, Kawahara M. A Suicide Switch Directly Eliminates Intracellular scFv Oligomers in the Cytoplasm of Mammalian Cells. Biotechnol J. 2019;14:e1800350 pubmed publisher
Mostafa H, Thompson T, Konen A, Haenchen S, Hilliard J, Macdonald S, et al. Herpes Simplex Virus 1 Mutant with Point Mutations in UL39 Is Impaired for Acute Viral Replication in Mice, Establishment of Latency, and Explant-Induced Reactivation. J Virol. 2018;92: pubmed publisher
Rehker J, Rodhe J, Nesbitt R, Boyle E, Martin B, Lord J, et al. Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants. PLoS ONE. 2017;12:e0185777 pubmed publisher
Weaver B, Weaver Y, Mitani S, Han M. Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Dev Cell. 2017;41:665-673.e6 pubmed publisher
Waldron Roby E, Hoerauf J, Arbez N, Zhu S, KULCSAR K, Ross C. Sox11 Reduces Caspase-6 Cleavage and Activity. PLoS ONE. 2015;10:e0141439 pubmed publisher
Li Y, Qian X, Yu Y, Li Z, Wu R, Ji J, et al. EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy. Oncotarget. 2015;6:17491-500 pubmed
Stennicke H, Salvesen G. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem. 1997;272:25719-23 pubmed
product information
Catalog Number :
11817
Product Name :
pcDNA3-Casp8
article :
doi10.1074/jbc.272.41.25719
id671
pubmed_id9325297
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5KpnI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
geneCASP8
id841
genbank_ids
mutation
nameCaspase 8
shRNA_sequence
size1550
species
9606
Homo sapiens
tags
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA