This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Casp3 C163A-myc
catalog :
11814
citations: 7
Reference
Al Moussawi K, Chung K, Carroll T, Osterburg C, Smirnov A, Lotz R, et al. Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis. Cell Rep. 2022;41:111503 pubmed publisher
Eichler M, Distler U, Nasrullah U, Krishnan A, Kaulich M, Husnjak K, et al. The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions. Cell Death Dis. 2022;13:386 pubmed publisher
Ivanova S, Polajnar M, Narbona Pérez Á, Hernández Alvarez M, Frager P, Slobodnyuk K, et al. Regulation of death receptor signaling by the autophagy protein TP53INP2. EMBO J. 2019;38: pubmed publisher
Khatri N, Gilbert J, Huo Y, Sharaflari R, Nee M, Qiao H, et al. The Autism Protein Ube3A/E6AP Remodels Neuronal Dendritic Arborization via Caspase-Dependent Microtubule Destabilization. J Neurosci. 2018;38:363-378 pubmed publisher
Wang Y, Wang X, Flores E, Yu J, Chang S. Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation. Aging Cell. 2016;15:646-60 pubmed publisher
Sarkar A, Balakrishnan K, Chen J, Patel V, Neelapu S, McMurray J, et al. Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma. Oncotarget. 2016;7:3461-76 pubmed publisher
Stennicke H, Salvesen G. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem. 1997;272:25719-23 pubmed
product information
Catalog Number :
11814
Product Name :
pcDNA3-Casp3 C163A-myc
article :
doi10.1074/jbc.272.41.25719
id671
pubmed_id9325297
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Caspase 3
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5KpnI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCPP32, CPP32B, SCA-1
geneCASP3
id836
genbank_ids
mutationC163A
nameCaspase 3 catalytic mutant
shRNA_sequence
size950
species
9606
Homo sapiens
tags
locationC terminal on insert
tagMyc
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA