This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Casp3-myc
catalog :
11813
citations: 8
Reference
Al Moussawi K, Chung K, Carroll T, Osterburg C, Smirnov A, Lotz R, et al. Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis. Cell Rep. 2022;41:111503 pubmed publisher
Eichler M, Distler U, Nasrullah U, Krishnan A, Kaulich M, Husnjak K, et al. The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions. Cell Death Dis. 2022;13:386 pubmed publisher
Cheng Q, Dai Z, Shi X, Duan X, Wang Y, Hou T, et al. Expanding the toolbox of exosome-based modulators of cell functions. Biomaterials. 2021;277:121129 pubmed publisher
Nader M, Khalil B, Kattuah W, Dzimiri N, Bakheet D. Striatin translocates to the cytosol of apoptotic cells and is proteolytically cleaved in a caspase 3-dependent manner. Heliyon. 2020;6:e04990 pubmed publisher
Backes C, Friedmann K, Mang S, Knörck A, Hoth M, Kummerow C. Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms. J Biol Chem. 2018;293:16348-16363 pubmed publisher
Weaver B, Weaver Y, Mitani S, Han M. Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Dev Cell. 2017;41:665-673.e6 pubmed publisher
Sarkar A, Balakrishnan K, Chen J, Patel V, Neelapu S, McMurray J, et al. Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma. Oncotarget. 2016;7:3461-76 pubmed publisher
Stennicke H, Salvesen G. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem. 1997;272:25719-23 pubmed
product information
Catalog Number :
11813
Product Name :
pcDNA3-Casp3-myc
article :
doi10.1074/jbc.272.41.25719
id671
pubmed_id9325297
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3BGH-rev; Sp6
sequencing_primer_5CMV-F; T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCPP32, CPP32B, SCA-1
geneCASP3
id836
genbank_ids
mutation
nameCaspase 3
shRNA_sequence
size983
species
9606
Homo sapiens
tags
locationC terminal on insert
tagMyc
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA