This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-Casp2-Flag
catalog :
11811
citations: 7
Reference
Li J, Chen C, O Neill K, Fousek Schuller V, Black A, Black J, et al. Combined inhibition of Aurora Kinases and Bcl-xL induces apoptosis through select BH3-only proteins. J Biol Chem. 2023;:102875 pubmed publisher
Eichler M, Distler U, Nasrullah U, Krishnan A, Kaulich M, Husnjak K, et al. The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions. Cell Death Dis. 2022;13:386 pubmed publisher
H Dehkordi M, Tashakor A, O Connell E, Fearnhead H. Apoptosome-dependent myotube formation involves activation of caspase-3 in differentiating myoblasts. Cell Death Dis. 2020;11:308 pubmed publisher
Pham D, Bruelle C, Thi Do H, Pajanoja C, Jin C, Srinivasan V, et al. Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells. Cell Death Dis. 2019;10:537 pubmed publisher
Kalabova D, Smidova A, Petrvalska O, Alblova M, Kosek D, Man P, et al. Human procaspase-2 phosphorylation at both S139 and S164 is required for 14-3-3 binding. Biochem Biophys Res Commun. 2017;493:940-945 pubmed publisher
Weaver B, Weaver Y, Mitani S, Han M. Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development. Dev Cell. 2017;41:665-673.e6 pubmed publisher
Imre G, Berthelet J, Heering J, Kehrloesser S, Melzer I, Lee B, et al. Apoptosis inhibitor 5 is an endogenous inhibitor of caspase-2. EMBO Rep. 2017;18:733-744 pubmed publisher
product information
Catalog Number :
11811
Product Name :
pcDNA3-Casp2-Flag
article :
doi
id672
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3Don't know
cloning_site_5Don't know
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCASP-2, ICH1, MRT80, NEDD-2, NEDD2, PPP1R57
geneCASP2
id835
genbank_ids
mutation
nameCaspase-2
shRNA_sequence
size1433
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFLAG
resistance markers :
435
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA