This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
p426 25Q GPD
catalog :
1181
citations: 5
Reference
Pradhan S, Rao K, Manjunath M, Saiswaroop R, Patnana D, Phalguna K, et al. Vitamin B6, B12 and folate modulate deregulated pathways and protein aggregation in yeast model of Huntington disease. 3 Biotech. 2023;13:96 pubmed publisher
Machida K, Shigeta T, Kobayashi A, Masumoto A, Hidaka Y, Imataka H. Cell-free analysis of polyQ-dependent protein aggregation and its inhibition by chaperone proteins. J Biotechnol. 2016;239:1-8 pubmed publisher
Chen Y, Bharill S, O HAGAN R, Isacoff E, Chalfie M. MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans. G3 (Bethesda). 2016;6:1121-30 pubmed publisher
Gamerdinger M, Hajieva P, Kaya A, Wolfrum U, Hartl F, Behl C. Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3. EMBO J. 2009;28:889-901 pubmed publisher
Krobitsch S, Lindquist S. Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. Proc Natl Acad Sci U S A. 2000;97:1589-94 pubmed
product information
Catalog Number :
1181
Product Name :
p426 25Q GPD
article :
doi10.1073/pnas.97.4.1589
id29
pubmed_id10677504
bacterial resistance :
Ampicillin
cloning :
backbonep426 GPD
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Yeast Expression
growth notes :
N terminal region of Ht with polyQ repeat length of 25 fused to GFP.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3EGFP-N
sequencing_primer_5M13R
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHD, IT15, LOMARS
geneHTT
id3064
genbank_ids
NM_002111
mutation
namehtt 25Q
shRNA_sequence
size250
species
9606
Homo sapiens
tags
locationC terminal on insert
tagGFP
resistance markers :
293
tags :
High Copy
terms :
URA3
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA