This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLX313-TP53-WT
catalog :
118014
citations: 3
Reference
V xe1 vra J, Sergunin A, Pompach P, Savchenko D, Hran xed x10d ek J, x160 loufov xe1 I, et al. Characterization of the interaction between the tumour suppressor p53 and heme and its role in the protein conformational dynamics studied by various spectroscopic techniques and hydrogen/deuterium exchange coupled with mass spectrometry. J Inorg Biochem. 2023;243:112180 pubmed publisher
Wang Y, Goh K, Chen Z, Lee W, Choy S, Fong J, et al. A Novel TP53 Gene Mutation Sustains Non-Small Cell Lung Cancer through Mitophagy. Cells. 2022;11: pubmed publisher
Giacomelli A, Yang X, Lintner R, McFarland J, Duby M, Kim J, et al. Mutational processes shape the landscape of TP53 mutations in human cancer. Nat Genet. 2018;50:1381-1387 pubmed publisher
product information
Catalog Number :
118014
Product Name :
pLX313-TP53-WT
article :
doi10.1038/s41588-018-0204-y
id28196696
pubmed_id30224644
bacterial resistance :
Ampicillin
cloning :
backbonepLX313
backbone_mutation
backbone_originBroad Institute
backbone_size8767
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
Constitutive expression of wild-type human Tumor Protein p53 (TP53)
origin :
37
pi :
alt_names
cloning
clone_methodGateway Cloning
cloning_site_3
cloning_site_5
promoterEF1alpha
sequencing_primer_3WPRE
sequencing_primer_5EF1alpha
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutation
nameTP53
shRNA_sequence
size1257
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagV5
resistance markers :
184
423
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA