pCMV5B-TGFbeta receptor I K232R | Addgene 11763 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pCMV5B-TGFbeta receptor I K232R

catalog :

11763

citations: 4

Reference
Melendez J, Sieiro D, Salgado D, Morin V, Dejardin M, Zhou C, et al. TGFβ signalling acts as a molecular brake of myoblast fusion. Nat Commun. 2021;12:749 pubmed publisher
Predes D, Cruz J, Abreu J, Mendes F. CUB domain-containing protein 1 (CDCP1) binds transforming growth factor beta family members and increase TGF-β1 signaling pathway. Exp Cell Res. 2019;383:111499 pubmed publisher
Kim S, Ham S, Yang K, Kim K. Protein kinase CK2 activation is required for transforming growth factor β-induced epithelial-mesenchymal transition. Mol Oncol. 2018;12:1811-1826 pubmed publisher
Wieser R, Wrana J, Massague J. GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex. EMBO J. 1995;14:2199-208 pubmed

product information

Catalog Number :

11763

Product Name :

pCMV5B-TGFbeta receptor I K232R

article :

doi
id	638
pubmed_id	7774578

bacterial resistance :

Ampicillin

cloning :

backbone

pCMV5B

backbone_mutation

backbone_origin

backbone_size

4700

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	BamHI
cloning_site_5	HindIII
promoter	CMV
sequencing_primer_3	hGHpA-R
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TBR-i, TBRI, TGFR-1, tbetaR-I
gene	TGFBR1
id	7046

genbank_ids

NM_004612

mutation

K232R: kinase dead

name

TGFbeta receptor I

shRNA_sequence

size

1600

species

9606

Homo sapiens