This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV5B-TFGbeta receptor II K277R
catalog :
11762
citations: 2
Reference
Melendez J, Sieiro D, Salgado D, Morin V, Dejardin M, Zhou C, et al. TGFβ signalling acts as a molecular brake of myoblast fusion. Nat Commun. 2021;12:749 pubmed publisher
Wrana J, Attisano L, Carcamo J, Zentella A, Doody J, Laiho M, et al. TGF beta signals through a heteromeric protein kinase receptor complex. Cell. 1992;71:1003-14 pubmed
product information
Catalog Number :
11762
Product Name :
pCMV5B-TFGbeta receptor II K277R
article :
doi10.1016/0092-8674(92)90395-S
id656
pubmed_id1333888
bacterial resistance :
Ampicillin
cloning :
backbonepCMV5B
backbone_mutation
backbone_origin
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5KpnI
promoterCMV
sequencing_primer_3hGHpA-R
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII, tbetaR-II
geneTGFBR2
id7048
genbank_ids
NM_003242
mutationK277R: kinase dead
nameTGFbeta receptor II
shRNA_sequence
size1800
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHis
plasmid copy :
This plasmid was constructed at the Massague lab at MSKCC. Please acknowledge both the Wrana and Massague labs in your publication.
resistance markers :
313
589
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA