pHAGE-PIK3CA-E545K | Addgene 116485 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pHAGE-PIK3CA-E545K

catalog :

116485

citations: 3

Reference
Aw W, Cho C, Wang H, Cooper A, Doherty E, Rocco D, et al. Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation. Sci Adv. 2023;9:eade8939 pubmed publisher
Chan C, Chiou L, Lee T, Liu Y, Hsieh T, Yang C, et al. PAK and PI3K pathway activation confers resistance to KRASG12C inhibitor sotorasib. Br J Cancer. 2023;128:148-159 pubmed publisher
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher

product information

Catalog Number :

116485

Product Name :

pHAGE-PIK3CA-E545K

article :

doi	10.1016/j.ccell.2018.01.021
id	28196511
pubmed_id	29533785

bacterial resistance :

Ampicillin

cloning :

backbone

pHAGE

backbone_mutation

backbone_origin

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Lentiviral

growth strain :

Lentiviral expression of PIK3CA E545K

inserts :

Stbl3

origin :

pi :

alt_names

cloning

clone_method	Gateway Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	CCM4, CLAPO, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, PI3K-alpha, p110-alpha
gene	PIK3CA
id	5290

genbank_ids

mutation

E545K

name

PIK3CA

shRNA_sequence

size

species

9606

Homo sapiens