This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3-HA-ADH
catalog :
11610
citations: 5
Reference
Schoenfeld D, Zhou R, Zairis S, Su W, Steinbach N, Mathur D, et al. Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma. Mol Cancer Res. 2022;: pubmed publisher
Voronkova M, Rojanasakul L, Kiratipaiboon C, Rojanasakul Y. The SOX9-Aldehyde Dehydrogenase Axis Determines Resistance to Chemotherapy in Non-Small-Cell Lung Cancer. Mol Cell Biol. 2020;40: pubmed publisher
Solomon H, Dinowitz N, Pateras I, Cooks T, Shetzer Y, Molchadsky A, et al. Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers. Oncogene. 2018;37:1669-1684 pubmed publisher
Gasparetto M, Pei S, Minhajuddin M, Khan N, Pollyea D, Myers J, et al. Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1. Haematologica. 2017;102:1054-1065 pubmed publisher
Wang J, Nikhil K, Viccaro K, Chang L, White J, Shah K. Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer. BMC Biol. 2017;15:10 pubmed publisher
product information
Catalog Number :
11610
Product Name :
pcDNA3-HA-ADH
article :
doi
id619
pubmed_id
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3-HA
backbone_mutation
backbone_origininvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
ALDH1
cloning
clone_methodRestriction Enzyme
cloning_site_3Xba I
cloning_site_5Hind III
promoter
sequencing_primer_3SP6
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1
geneALDH1A1
id216
genbank_ids
NM_000689
mutationK412I
namealdehyde dehydrogenase
shRNA_sequence
size1505
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
resistance markers :
232
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA