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product summary
company name :
Addgene
product type :
cDNA
product name :
EGFP-LC3
catalog :
11546
citations: 144
Reference
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Bu X, Zhang J, Sun H, Wang W, Ma X, Sun L. SEC61 translocon subunit gamma enhances low-dose cisplatin-induced cancer-stem cell properties of head and neck squamous cell carcinoma via enhancing Ca2+-mediated autophagy. J Dent Sci. 2023;18:1685-1692 pubmed publisher
Ou M, Cho H, Fu J, Thein T, Wang W, Swenson S, et al. Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate. Autophagy. 2023;19:3169-3188 pubmed publisher
Geng F, Zhong Y, Su H, Lefai E, Magaki S, Cloughesy T, et al. SREBP-1 upregulates lipophagy to maintain cholesterol homeostasis in brain tumor cells. Cell Rep. 2023;42:112790 pubmed publisher
Zheng Z, Han L, Li Y, Chen Z, Yang W, Liu C, et al. Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization. Biochim Biophys Acta Mol Cell Res. 2023;1870:119487 pubmed publisher
Diao F, Jiang C, Sun Y, Gao Y, Bai J, Nauwynck H, et al. Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication. PLoS Pathog. 2023;19:e1011295 pubmed publisher
Quiles J, Najor R, Gonzalez E, Jeung M, Liang W, Burbach S, et al. Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy. Sci Signal. 2023;16:eabo4457 pubmed publisher
Liu N, Li M, Liu S, Kang J, Chen L, Huang J, et al. Exogenous H2S Attenuates Hypertension by Regulating Renin Exocytosis under Hyperglycaemic and Hyperlipidaemic Conditions. Int J Mol Sci. 2023;24: pubmed publisher
Bai Y, Yu G, Zhou H, Amarasinghe O, Zhou Y, Zhu P, et al. PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. Autophagy. 2022;:1-20 pubmed publisher
Hwang S, Kim H, Lee M. Paradoxical downregulation of LPAR3 exerts tumor-promoting activity through autophagy induction in Ras-transformed cells. BMC Cancer. 2022;22:969 pubmed publisher
Cocco S, Leone A, Roca M, Lombardi R, Piezzo M, Caputo R, et al. Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models. J Transl Med. 2022;20:290 pubmed publisher
Yu J, Han L, Yang F, Zhao M, Zhou H, Hu L. SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy. Bioengineered. 2022;13:14125-14137 pubmed publisher
Katiyar P, Banerjee S, Nathani S, Roy P. Triclosan-induced neuroinflammation develops caspase-independent and TNF-α signaling pathway associated necroptosis in Neuro-2a cells. Curr Res Toxicol. 2022;3:100072 pubmed publisher
Khan S, Ali M, Kabir F, Na C, Delannoy M, Ma Y, et al. The role of FYCO1-dependent autophagy in lens fiber cell differentiation. Autophagy. 2022;:1-18 pubmed publisher
Fan Y, Cheng Z, Mao L, Xu G, Li N, Zhang M, et al. PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles. J Nanobiotechnology. 2022;20:149 pubmed publisher
Miyakawa K, Nishi M, Ogawa M, Matsunaga S, Sugiyama M, Nishitsuji H, et al. Galectin-9 restricts hepatitis B virus replication via p62/SQSTM1-mediated selective autophagy of viral core proteins. Nat Commun. 2022;13:531 pubmed publisher
Wen Y, Chelariu Raicu A, Umamaheswaran S, Nick A, Stur E, Hanjra P, et al. Endothelial p130cas confers resistance to anti-angiogenesis therapy. Cell Rep. 2022;38:110301 pubmed publisher
Su W, YU X, Zhou C. SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response. Viruses. 2021;13: pubmed publisher
Wang C, Lin S, Huang Y, Hsieh C, Chang H, Chen H, et al. Paired-like homeodomain 2B contributes to tumour progression and anti-autophagy in human lung cancer. Am J Cancer Res. 2021;11:4900-4918 pubmed
Doke T, Huang S, Qiu C, Sheng X, Seasock M, Liu H, et al. Genome-wide association studies identify the role of caspase-9 in kidney disease. Sci Adv. 2021;7:eabi8051 pubmed publisher
Hu P, Li H, Sun W, Wang H, Yu X, Qing Y, et al. Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218. Acta Pharm Sin B. 2021;11:3178-3192 pubmed publisher
Relic B, Deroyer C, Malaise O, Plener Z, Gillet P, de Seny D, et al. TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells. Biochem J. 2021;478:3145-3155 pubmed publisher
García Miranda A, Solano Alcalá K, Montes Alvarado J, Rosas Cruz A, Reyes Leyva J, Navarro Tito N, et al. Autophagy Mediates Leptin-Induced Migration and ERK Activation in Breast Cancer Cells. Front Cell Dev Biol. 2021;9:644851 pubmed publisher
Vitale D, Caon I, Parnigoni A, Sevic I, Spinelli F, Icardi A, et al. Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells. Biomolecules. 2021;11: pubmed publisher
Yeom H, Hwang S, Han B, Lee M. Differential Sensitivity of Wild-Type and BRAF-Mutated Cells to Combined BRAF and Autophagy Inhibition. Biomol Ther (Seoul). 2021;29:434-444 pubmed publisher
Hu P, Wang J, Qing Y, Li H, Sun W, Yu X, et al. FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation. Cell Death Dis. 2021;12:80 pubmed publisher
Chen M, Gowd V, Wang M, Chen F, Cheng K. The apple dihydrochalcone phloretin suppresses growth and improves chemosensitivity of breast cancer cells via inhibition of cytoprotective autophagy. Food Funct. 2021;12:177-190 pubmed publisher
Sun T, Hu Y, He W, Shang Y, Yang X, Gong L, et al. SRT2183 impairs ovarian cancer by facilitating autophagy. Aging (Albany NY). 2020;12:24208-24218 pubmed publisher
Peláez Coyotl E, Barrios Palacios J, Muciño G, Moreno Blas D, Costas M, Montiel Montes T, et al. Antimicrobial Peptide against Mycobacterium Tuberculosis That Activates Autophagy Is an Effective Treatment for Tuberculosis. Pharmaceutics. 2020;12: pubmed publisher
Mao M, Chang C, Pickar Oliver A, Cervia L, Wang L, Ji J, et al. Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo. Adv Biosyst. 2020;4:e2000059 pubmed publisher
Naik P, Mukhopadhyay S, Praharaj P, Bhol C, Panigrahi D, Mahapatra K, et al. Secretory clusterin promotes oral cancer cell survival via inhibiting apoptosis by activation of autophagy in AMPK/mTOR/ULK1 dependent pathway. Life Sci. 2021;264:118722 pubmed publisher
Chen B, Chang Y, Lin S, Yang W. Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes. Nat Commun. 2020;11:5267 pubmed publisher
Wang S, Huang Y, Luo G, Yang X, Huang W. Cyanidin-3-O-glucoside attenuates high glucose-induced podocytes dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway. Can J Physiol Pharmacol. 2020;: pubmed publisher
Hwang S, Yeom H, Lee M. ATG5 knockout promotes paclitaxel sensitivity in drug-resistant cells via induction of necrotic cell death. Korean J Physiol Pharmacol. 2020;24:233-240 pubmed publisher
Dasari S, Bakthavachalam V, Chinnapaka S, Venkatesan R, Samy A, Munirathinam G. Neferine, an alkaloid from lotus seed embryo targets HeLa and SiHa cervical cancer cells via pro-oxidant anticancer mechanism. Phytother Res. 2020;34:2366-2384 pubmed publisher
Lee S, Kreuzenbeck N, Jang M, Oh T, Ko S, Ahn J, et al. Xyloneside A: A New Glycosylated Incisterol Derivative from Xylaria sp. FB. Chembiochem. 2020;: pubmed publisher
Feng X, Zhang H, Meng L, Song H, Zhou Q, Qu C, et al. Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5. Autophagy. 2020;:1-20 pubmed publisher
Castro Gonzalez S, Shi Y, Colomer Lluch M, Song Y, Mowery K, Almodovar S, et al. HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner. Autophagy. 2020;:1-25 pubmed publisher
Kwon M, Jang M, Kim G, Oh T, Ryoo I, Ryu H, et al. Kushenol E inhibits autophagy and impairs lysosomal positioning via VCP/p97 inhibition. Biochem Pharmacol. 2020;175:113861 pubmed publisher
Patra S, Panda P, Panigrahi D, Praharaj P, Bhol C, Mahapatra K, et al. Terminalia bellirica extract induces anticancer activity through modulation of apoptosis and autophagy in oral squamous cell carcinoma. Food Chem Toxicol. 2019;136:111073 pubmed publisher
You M, Miao Z, Tian J, Hu F. Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy. Eur J Nutr. 2019;: pubmed publisher
Liu X, Liao X, Rao X, Wang B, Zhang J, Xu G, et al. The lysosomal membrane protein LAMP-2 is dispensable for PINK1/Parkin-mediated mitophagy. FEBS Lett. 2020;594:823-840 pubmed publisher
Bao H, Zhang Q, Liu X, Song Y, Li X, Wang Z, et al. Lithium targeting of AMPK protects against cisplatin-induced acute kidney injury by enhancing autophagy in renal proximal tubular epithelial cells. FASEB J. 2019;33:14370-14381 pubmed publisher
Joshi D, Zhang C, Babujee L, Vevea J, August B, Sheng Z, et al. Inappropriate Intrusion of an Axonal Mitochondrial Anchor into Dendrites Causes Neurodegeneration. Cell Rep. 2019;29:685-696.e5 pubmed publisher
Takahashi D, Moriyama J, Nakamura T, Miki E, Takahashi E, Sato A, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019;76:797-810.e10 pubmed publisher
Guo S, Zhang L, Zhang Y, Wu Z, He D, Li X, et al. Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition. Aging (Albany NY). 2019;11:7553-7569 pubmed publisher
Hsieh C, Huang H, Chen K, Saka T, Chiang C, Chung L, et al. A Novel Salicylanilide Derivative Induces Autophagy Cell Death in Castration-Resistant Prostate Cancer via ER Stress-Activated PERK Signaling Pathway. Mol Cancer Ther. 2019;: pubmed publisher
Tang C, Han H, Liu Z, Liu Y, Yin L, Cai J, et al. Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury. Cell Death Dis. 2019;10:677 pubmed publisher
Wang K, Tu Y, Wan J, Chen M, He C. Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation. Carcinogenesis. 2019;: pubmed publisher
Juanes M, Isnardon D, Badache A, Brasselet S, Mavrakis M, Goode B. The role of APC-mediated actin assembly in microtubule capture and focal adhesion turnover. J Cell Biol. 2019;218:3415-3435 pubmed publisher
Schott M, Weller S, Schulze R, Krueger E, Drizyte Miller K, Casey C, et al. Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes. J Cell Biol. 2019;218:3320-3335 pubmed publisher
Zhen Y, Spangenberg H, Munson M, Brech A, Schink K, Tan K, et al. ESCRT-mediated phagophore sealing during mitophagy. Autophagy. 2019;:1-16 pubmed publisher
Njomen E, Tepe J. Regulation of Autophagic Flux by the 20S Proteasome. Cell Chem Biol. 2019;26:1283-1294.e5 pubmed publisher
Yu S, Wang X, Dou N, Zhou J, Gao Y, Li Y. B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma. Hepatol Res. 2019;49:1329-1340 pubmed publisher
Valencia Lopez M, Schimmeck H, Gropengießer J, Middendorf L, Quitmann M, Schneider C, et al. Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells. Cell Microbiol. 2019;:e13046 pubmed publisher
Thangaraj A, Periyasamy P, Guo M, Chivero E, Callen S, Buch S. Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics. Autophagy. 2019;:1-24 pubmed publisher
Kong Z, Liu R, Cheng Y. Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway. Biomed Pharmacother. 2019;109:2043-2053 pubmed publisher
Cummins N, Tweedie A, Zuryn S, Bertran Gonzalez J, Götz J. Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria. EMBO J. 2019;38: pubmed publisher
Sebori R, Kuno A, Hosoda R, Hayashi T, Horio Y. Resveratrol Decreases Oxidative Stress by Restoring Mitophagy and Improves the Pathophysiology of Dystrophin-Deficient mdx Mice. Oxid Med Cell Longev. 2018;2018:9179270 pubmed publisher
Sharif T, Martell E, Dai C, Ghassemi Rad M, Hanes M, Murphy P, et al. HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells. Autophagy. 2018;: pubmed publisher
Hu X, Mullins R. LC3 and STRAP regulate actin filament assembly by JMY during autophagosome formation. J Cell Biol. 2019;218:251-266 pubmed publisher
Seok J, Jeong Y, Hwang S, Kim C, Magae J, Chang Y. Upregulation of AMPK by 4-O-methylascochlorin promotes autophagy via the HIF-1α expression. J Cell Mol Med. 2018;22:6345-6356 pubmed publisher
Huang Z, Liu Y, Huang X. Formononetin may protect aged hearts from ischemia/reperfusion damage by enhancing autophagic degradation. Mol Med Rep. 2018;18:4821-4830 pubmed publisher
Kim K, Lee S, Baek S, Lee E, Jang E, Lee J, et al. Salinomycin ameliorates oxidative hepatic damage through AMP-activated protein kinase, facilitating autophagy. Toxicol Appl Pharmacol. 2018;360:141-149 pubmed publisher
Sharif T, Martell E, Dai C, Ghassemi Rad M, Lee K, Singh S, et al. Phosphoglycerate dehydrogenase inhibition induces p-mTOR-independent autophagy and promotes multilineage differentiation in embryonal carcinoma stem-like cells. Cell Death Dis. 2018;9:990 pubmed publisher
Satyavarapu E, Das R, Mandal C, Mukhopadhyay A, Mandal C. Autophagy-independent induction of LC3B through oxidative stress reveals its non-canonical role in anoikis of ovarian cancer cells. Cell Death Dis. 2018;9:934 pubmed publisher
Gu J, Wang Y, Wang X, Zhou D, Wang X, Zhou M, et al. Effect of the LncRNA GAS5-MiR-23a-ATG3 Axis in Regulating Autophagy in Patients with Breast Cancer. Cell Physiol Biochem. 2018;48:194-207 pubmed publisher
Thangaraj A, Periyasamy P, Liao K, Bendi V, Callen S, Pendyala G, et al. HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy. Autophagy. 2018;14:1596-1619 pubmed publisher
Ishida S, Akiyama H, Umezawa Y, Okada K, Nogami A, Oshikawa G, et al. Mechanisms for mTORC1 activation and synergistic induction of apoptosis by ruxolitinib and BH3 mimetics or autophagy inhibitors in JAK2-V617F-expressing leukemic cells including newly established PVTL-2. Oncotarget. 2018;9:26834-26851 pubmed publisher
Sun Y, Liu M, Lei X, YU X. SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins. Sci Rep. 2018;8:5287 pubmed publisher
HALL E, Ramsey J, Peng Z, Hayrapetyan D, Shkepu V, O Rourke B, et al. Novel organometallic chloroquine derivative inhibits tumor growth. J Cell Biochem. 2018;119:5921-5933 pubmed publisher
Döring T, Zeyen L, Bartusch C, Prange R. Hepatitis B Virus Subverts the Autophagy Elongation Complex Atg5-12/16L1 and Does Not Require Atg8/LC3 Lipidation for Viral Maturation. J Virol. 2018;92: pubmed publisher
Wong Y, Ysselstein D, Krainc D. Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis. Nature. 2018;554:382-386 pubmed publisher
Wu W, Schecker J, Würstle S, Schneider F, Schönfelder M, Schlegel J. Aldehyde dehydrogenase 1A3 (ALDH1A3) is regulated by autophagy in human glioblastoma cells. Cancer Lett. 2018;417:112-123 pubmed publisher
Wang B, Zhang J, Chen C, Xu G, Qin X, Hong Y, et al. The size of zinc oxide nanoparticles controls its toxicity through impairing autophagic flux in A549 lung epithelial cells. Toxicol Lett. 2018;285:51-59 pubmed publisher
Brothers K, Kowalski R, Tian S, Kinchington P, Shanks R. Bacteria induce autophagy in a human ocular surface cell line. Exp Eye Res. 2018;168:12-18 pubmed publisher
Hurwitz S, Cheerathodi M, Nkosi D, York S, Meckes D. Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1. J Virol. 2018;92: pubmed publisher
Rajput M, Abdelsalam K, Darweesh M, Braun L, Kerkvliet J, Hoppe A, et al. Both cytopathic and non-cytopathic bovine viral diarrhea virus (BVDV) induced autophagy at a similar rate. Vet Immunol Immunopathol. 2017;193-194:1-9 pubmed publisher
Ansari M, Khan N, Haqqi T. A standardized extract of Butea monosperma (Lam.) flowers suppresses the IL-1?-induced expression of IL-6 and matrix-metalloproteases by activating autophagy in human osteoarthritis chondrocytes. Biomed Pharmacother. 2017;96:198-207 pubmed publisher
Kemp V, Dautzenberg I, Limpens R, van den Wollenberg D, Hoeben R. Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery. Viruses. 2017;9: pubmed publisher
Kim S, Kim G, Han D, Lee M, Kim I, Kim B, et al. Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition. Autophagy. 2017;13:1767-1781 pubmed publisher
Balboa D, Weltner J, Novik Y, Eurola S, Wartiovaara K, Otonkoski T. Generation of an OCT4 reporter human induced pluripotent stem cell line using CRISPR/SpCas9. Stem Cell Res. 2017;23:105-108 pubmed publisher
Merrill N, Schipper J, Karnes J, Kauffman A, Martin K, Mackeigan J. PI3K-C2? knockdown decreases autophagy and maturation of endocytic vesicles. PLoS ONE. 2017;12:e0184909 pubmed publisher
Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;37: pubmed publisher
Park H, Ryu D, Parmar M, Giasson B, McFarland N. The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome. PLoS ONE. 2017;12:e0184262 pubmed publisher
Jiang X, Bao Y, Liu H, Kou X, Zhang Z, Sun F, et al. VPS34 stimulation of p62 phosphorylation for cancer progression. Oncogene. 2017;36:6850-6862 pubmed publisher
Das D, Naik P, Mukhopadhyay S, Panda P, Sinha N, Meher B, et al. Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis. Free Radic Biol Med. 2017;112:452-463 pubmed publisher
Nguyen T, Seo E, Choi J, Le O, Kim J, Jou I, et al. Phosphatidylinositol 4-phosphate 5-kinase α contributes to Toll-like receptor 2-mediated immune responses in microglial cells stimulated with lipoteichoic acid. Cell Signal. 2017;38:159-170 pubmed publisher
Cao B, Parnell L, Diamond M, Mysorekar I. Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice. J Exp Med. 2017;214:2303-2313 pubmed publisher
Dagda R, Rice M. Protocols for assessing mitophagy in neuronal cell lines and primary neurons. Neuromethods. 2017;123:249-277 pubmed publisher
Chang S, Huang S, Wang S, Chung K, Hsieh C, Kao J, et al. Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells. J Dermatol Sci. 2017;87:138-148 pubmed publisher
Mazzuca P, Marsico S, Schulze K, Mitola S, Pils M, Giagulli C, et al. Role of Autophagy in HIV-1 Matrix Protein p17-Driven Lymphangiogenesis. J Virol. 2017;91: pubmed publisher
Zhu L, Guo D, Sun L, Huang Z, Zhang X, Ma W, et al. Activation of autophagy by elevated reactive oxygen species rather than released silver ions promotes cytotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in hematopoietic cells. Nanoscale. 2017;9:5489-5498 pubmed publisher
Bravo San Pedro J, Pietrocola F, Sica V, Izzo V, Sauvat A, Kepp O, et al. High-Throughput Quantification of GFP-LC3+ Dots by Automated Fluorescence Microscopy. Methods Enzymol. 2017;587:71-86 pubmed publisher
Gade T, Tucker E, Nakazawa M, Hunt S, Wong W, Krock B, et al. Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma. Radiology. 2017;283:702-710 pubmed publisher
Tavera Mendoza L, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, et al. Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells. Proc Natl Acad Sci U S A. 2017;114:E2186-E2194 pubmed publisher
Varshney R, Gupta S, Roy P. Cytoprotective effect of kaempferol against palmitic acid-induced pancreatic ?-cell death through modulation of autophagy via AMPK/mTOR signaling pathway. Mol Cell Endocrinol. 2017;448:1-20 pubmed publisher
Zummo F, Cullen K, Honkanen Scott M, Shaw J, Lovat P, Arden C. Glucagon-Like Peptide 1 Protects Pancreatic ?-Cells From Death by Increasing Autophagic Flux and Restoring Lysosomal Function. Diabetes. 2017;66:1272-1285 pubmed publisher
Chen P, Luo X, Nie P, Wu B, Xu W, Shi X, et al. CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk. Free Radic Biol Med. 2017;104:280-297 pubmed publisher
Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
Kim H, Lee S, Kim C, Kim Y, Ju W, Kim S. Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells. Oncotarget. 2017;8:6608-6622 pubmed publisher
Balasubramanian A, Teramoto T, Kulkarni A, Bhattacharjee A, Padmanabhan R. Antiviral activities of selected antimalarials against dengue virus type 2 and Zika virus. Antiviral Res. 2017;137:141-150 pubmed publisher
Dias M, Teixeira B, Rodrigues B, Sinigaglia Coimbra R, Porto Carreiro I, Roffe M, et al. PRNP/prion protein regulates the secretion of exosomes modulating CAV1/caveolin-1-suppressed autophagy. Autophagy. 2016;12:2113-2128 pubmed
Ali M, Devkota S, Roh J, Lee J, Lee H. Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1. Biochem Biophys Res Commun. 2016;478:1198-204 pubmed publisher
García Aguilar A, Guillen C, Nellist M, Bartolomé A, Benito M. TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy. Biochim Biophys Acta. 2016;1863:2658-2667 pubmed publisher
Das D, Naik P, Nayak A, Panda P, Mukhopadhyay S, Sinha N, et al. Bacopa monnieri-Induced Protective Autophagy Inhibits Benzo[a]pyrene-Mediated Apoptosis. Phytother Res. 2016;30:1794-1801 pubmed publisher
Lin K, Cheng S, Tsai S, Tsai J, Lin C, Cheung C. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016;9:2601-13 pubmed publisher
Ra E, Lee T, Won Kim S, Park A, Choi H, Jang I, et al. TRIM31 promotes Atg5/Atg7-independent autophagy in intestinal cells. Nat Commun. 2016;7:11726 pubmed publisher
Panda P, Behera B, Meher B, Das D, Mukhopadhyay S, Sinha N, et al. Abrus Agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death. Mol Carcinog. 2017;56:389-401 pubmed publisher
Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed publisher
Bauckman K, Mysorekar I. Ferritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells. Autophagy. 2016;12:850-63 pubmed publisher
Wang Y, Kuramitsu Y, Baron B, Kitagawa T, Tokuda K, Akada J, et al. CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways. Oncotarget. 2015;6:39692-701 pubmed publisher
Modernelli A, Naponelli V, Giovanna Troglio M, Bonacini M, Ramazzina I, Bettuzzi S, et al. EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism. Sci Rep. 2015;5:15270 pubmed publisher
Hasanain M, Bhattacharjee A, Pandey P, Ashraf R, Singh N, Sharma S, et al. α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway. Cell Death Dis. 2015;6:e1860 pubmed publisher
Yen C, Chiang W, Liu S, Lin C, Liao K, Lin C, et al. Impacts of autophagy-inducing ingredient of areca nut on tumor cells. PLoS ONE. 2015;10:e0128011 pubmed publisher
Erie C, Sacino M, Houle L, Lu M, Wei J. Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease. Eur J Neurosci. 2015;42:1941-51 pubmed publisher
Liu C, Deroo E, Stecyk C, Wolsey M, Szuchnicki M, Hagos E. Impaired autophagy in mouse embryonic fibroblasts null for Krüppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation. Mol Cancer. 2015;14:101 pubmed publisher
Guo S, Liang Y, Murphy S, Huang A, Shen H, Kelly D, et al. A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications. Autophagy. 2015;11:560-72 pubmed publisher
Bauckman K, Haller E, Taran N, Rockfield S, Ruiz Rivera A, Nanjundan M. Iron alters cell survival in a mitochondria-dependent pathway in ovarian cancer cells. Biochem J. 2015;466:401-13 pubmed publisher
Wen Y, Graybill W, Previs R, Hu W, Ivan C, Mangala L, et al. Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer. Clin Cancer Res. 2015;21:448-59 pubmed publisher
Chen S, Zhang Y, Zhou L, Leng Y, Lin H, Kmieciak M, et al. A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis. Blood. 2014;124:2687-97 pubmed publisher
Panda P, Mukhopadhyay S, Behera B, Bhol C, Dey S, Das D, et al. Antitumor effect of soybean lectin mediated through reactive oxygen species-dependent pathway. Life Sci. 2014;111:27-35 pubmed publisher
Ram B, Ramakrishna G. Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition. Biochim Biophys Acta. 2014;1843:2497-512 pubmed publisher
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product information
Catalog Number :
11546
Product Name :
EGFP-LC3
article :
doi10.1371/journal.pbio.0030156
id604
pubmed_id15884975
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C3
backbone_mutation
backbone_originClontech
backbone_size4727
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
NM_022818
Human homolog of yeast ATG8p
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3EBV Reverse
sequencing_primer_5CMV Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a
geneMAP1LC3B
id81631
genbank_ids
NM_022818
mutation
nameLC3B
shRNA_sequence
size380
species
9606
Homo sapiens
tags
locationN terminal on insert
tagEGFP
plasmid copy :
Kopito Lab - see reference
resistance markers :
255
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA