This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pSV human p85 alpha (HA tag)
catalog :
11499
citations: 5
Reference
Ruiz Sáenz A, Dreyer C, Campbell M, Steri V, Gulizia N, Moasser M. HER2 Amplification in Tumors Activates PI3K/Akt Signaling Independent of HER3. Cancer Res. 2018;78:3645-3658 pubmed publisher
Masters T, Tumbarello D, Chibalina M, Buss F. MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics. Cell Rep. 2017;19:2088-2101 pubmed publisher
Ruch T, Bryant D, Mostov K, Engel J. Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity. Mol Biol Cell. 2017;28:252-260 pubmed publisher
Subbarayal P, Karunakaran K, Winkler A, Rother M, Gonzalez E, Meyer T, et al. EphrinA2 receptor (EphA2) is an invasion and intracellular signaling receptor for Chlamydia trachomatis. PLoS Pathog. 2015;11:e1004846 pubmed publisher
Cipriano R, Miskimen K, Bryson B, Foy C, Bartel C, Jackson M. FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Oncotarget. 2013;4:729-38 pubmed
product information
Catalog Number :
11499
Product Name :
pSV human p85 alpha (HA tag)
article :
doi10.1074/jbc.M305602200
id576
pubmed_id14504291
bacterial resistance :
Ampicillin
cloning :
backbonepSV Sport
backbone_mutation
backbone_origin
backbone_size3160
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
There is a short insert of aa (ENFLSCLPS) in the middle of the ORF compared to NCBI.
origin :
37
pi :
alt_names
PI3K regulatory subunit p85alpha
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5EcoRI
promoter
sequencing_primer_3T7
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAGM7, GRB1, IMD36, p85, p85-ALPHA, p85alpha
genePIK3R1
id5295
genbank_ids
mutation
namep85 alpha
shRNA_sequence
size2200
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHA
resistance markers :
240
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA