This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA-HA-Nedd4/2795
catalog :
11426
citations: 6
Reference
Sun L, Amraei R, Rahimi N. NEDD4 regulates ubiquitination and stability of the cell adhesion molecule IGPR-1 via lysosomal pathway. J Biomed Sci. 2021;28:35 pubmed publisher
Liu Q, Zhang S, Chen G, Zhou H. E3 ubiquitin ligase Nedd4 inhibits AP-1 activity and TNF-α production through targeting p38α for polyubiquitination and subsequent degradation. Sci Rep. 2017;7:4521 pubmed publisher
Gautam V, Trinidad J, Rimerman R, Costa B, Burlingame A, Monaghan D. Nedd4 is a specific E3 ubiquitin ligase for the NMDA receptor subunit GluN2D. Neuropharmacology. 2013;74:96-107 pubmed publisher
Dumaresq Doiron K, Jules F, Lefrancois S. Sortilin turnover is mediated by ubiquitination. Biochem Biophys Res Commun. 2013;433:90-5 pubmed publisher
Pilecka I, Sadowski L, Kalaidzidis Y, Miaczynska M. Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment. Exp Cell Res. 2011;317:1093-107 pubmed publisher
Magnifico A, Ettenberg S, Yang C, Mariano J, Tiwari S, Fang S, et al. WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation. J Biol Chem. 2003;278:43169-77 pubmed
product information
Catalog Number :
11426
Product Name :
pcDNA-HA-Nedd4/2795
article :
doi10.1074/jbc.M308009200
id488
pubmed_id12907674
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1(-)
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
Nedd4
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoR I
cloning_site_5Not I
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAA959633, AL023035, AU019897, E430025J12Rik, EG639396, Gm7265, KIAA0093, Nedd4-1, Nedd4a
geneNedd4
id17999
genbank_ids
U96635
mutationD661N compared to GenBank reference sequence U96635
nameNedd4-1
shRNA_sequence
size2000
species
10090
Mus musculus
tags
locationN terminal on insert
tagHA
resistance markers :
571
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA