This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
VP16-ER alpha
catalog :
11351
citations: 13
Reference
Bayele H. A conserved mechanism of sirtuin signalling through steroid hormone receptors. Biosci Rep. 2019;39: pubmed publisher
Kühnle S, Martinez Noel G, Leclere F, Hayes S, Harper J, Howley P. Angelman syndrome-associated point mutations in the Zn2+-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome. J Biol Chem. 2018;293:18387-18399 pubmed publisher
Sett A, Borthakur B, Sharma J, Kataki A, Bora U. DNA aptamer probes for detection of estrogen receptor α positive carcinomas. Transl Res. 2017;183:104-120.e2 pubmed publisher
Wright P, Jones S, Ardern N, Ward R, Clarke R, Sotgia F, et al. 17?-estradiol regulates giant vesicle formation via estrogen receptor-alpha in human breast cancer cells. Oncotarget. 2014;5:3055-65 pubmed
Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed
Pitta C, Papageorgis P, Charalambous C, Constantinou A. Reversal of ER-? silencing by chromatin modifying agents overrides acquired tamoxifen resistance. Cancer Lett. 2013;337:167-76 pubmed publisher
Kalthoff S, Winkler A, Freiberg N, Manns M, Strassburg C. Gender matters: estrogen receptor alpha (ER?) and histone deacetylase (HDAC) 1 and 2 control the gender-specific transcriptional regulation of human uridine diphosphate glucuronosyltransferases genes (UGT1A). J Hepatol. 2013;59:797-804 pubmed publisher
Brasseur K, Leblanc V, Fabi F, Parent S, Descôteaux C, Bérubé G, et al. ER?-targeted therapy in ovarian cancer cells by a novel estradiol-platinum(II) hybrid. Endocrinology. 2013;154:2281-95 pubmed publisher
Lucchetti C, Caligiuri I, Toffoli G, Giordano A, Rizzolio F. The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor ? in breast cancer. PLoS ONE. 2013;8:e55355 pubmed publisher
Harrison H, Rogerson L, Gregson H, Brennan K, Clarke R, Landberg G. Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-? status. Cancer Res. 2013;73:1420-33 pubmed publisher
Chandrasekharan S, Bhaskar B, Muthiah R, Chandrasekharan A, Ramamurthy V. Estrogenic effect of three substituted deoxybenzoins. Steroids. 2013;78:147-55 pubmed publisher
Chan H, Chang S, Wang T, Ko H, Lin Y, Lin K, et al. Serine protease PRSS23 is upregulated by estrogen receptor ? and associated with proliferation of breast cancer cells. PLoS ONE. 2012;7:e30397 pubmed publisher
Chang C, Norris J, Grøn H, Paige L, Hamilton P, Kenan D, et al. Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta. Mol Cell Biol. 1999;19:8226-39 pubmed
product information
Catalog Number :
11351
Product Name :
VP16-ER alpha
article :
doi
id520
pubmed_id10567548
bacterial resistance :
Ampicillin
cloning :
backbonepVP16
backbone_mutation
backbone_originClontech
backbone_size3300
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5EcoRI
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5SV40pro-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesER, ESR, ESRA, ESTRR, Era, NR3A1
geneESR1
id2099
genbank_ids
mutation
nameER alpha
shRNA_sequence
size1800
species
9606
Homo sapiens
tags
resistance markers :
321
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA