hCathepsin L | Addgene 11250 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

hCathepsin L

catalog :

11250

citations: 4

Reference
Pastorio C, Noettger S, Nchioua R, Zech F, Sparrer K, Kirchhoff F. Impact of mutations defining SARS-CoV-2 Omicron subvariants BA.2.12.1 and BA.4/5 on Spike function and neutralization. iScience. 2023;26:108299 pubmed publisher
Kim M, Jeong H, Krainc D. Lysosomal ceramides regulate Cathepsin B-mediated processing of saposin C and glucocerebrosidase activity. Hum Mol Genet. 2022;: pubmed publisher
Wang Y, Xu C, Ma L, Mou Y, Zhang B, Zhou S, et al. Drug screening with human SMN2 reporter identifies SMN protein stabilizers to correct SMA pathology. Life Sci Alliance. 2019;2: pubmed publisher
Huang I, Bosch B, Li F, Li W, Lee K, Ghiran S, et al. SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem. 2006;281:3198-203 pubmed

product information

Catalog Number :

11250

Product Name :

hCathepsin L

article :

doi	10.1074/jbc.M508381200
id	504
pubmed_id	16339146

bacterial resistance :

Ampicillin

cloning :

backbone

pcDNA3.1(-)

backbone_mutation

backbone_origin

Invitrogen

backbone_size

5428

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

See author's map for more information.

growth strain :

Mammalian expression of human cathepsin L

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	PmeI
cloning_site_5	XbaI
promoter
sequencing_primer_3
sequencing_primer_5	T7
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	CATL, CTSL1, MEP
gene	CTSL
id	1514

genbank_ids

mutation

name

cathepsin L

shRNA_sequence

size

species

9606

Homo sapiens