This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA cyclin D1 HA
catalog :
11181
citations: 8
Reference
B xe9 langer F, Roussel C, Sawchyn C, St Hilaire E, Gezzar Dandashi S, Kimenyi Ishimwe A, et al. A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21. J Biol Chem. 2023;299:104900 pubmed publisher
Samara A, Shapira S, Lubin I, Shpilberg O, Avigad S, Granot G, et al. Deferasirox induces cyclin D1 degradation and apoptosis in mantle cell lymphoma in a reactive oxygen species- and GSK3β-dependent mechanism. Br J Haematol. 2021;: pubmed publisher
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
Choi C, Park S, Cho W, Choi D. Cyclin D1 is Associated with Radiosensitivity of Triple-Negative Breast Cancer Cells to Proton Beam Irradiation. Int J Mol Sci. 2019;20: pubmed publisher
Yu S, Lee D, Baek S, Cho D, Choi J, Kang J. Identification of mTOR inhibitor-resistant genes in cutaneous squamous cell carcinoma. Cancer Manag Res. 2018;10:6379-6389 pubmed publisher
Wang N, Wang X, Tan H, Li S, Tsang C, Tsao S, et al. Berberine Suppresses Cyclin D1 Expression through Proteasomal Degradation in Human Hepatoma Cells. Int J Mol Sci. 2016;17: pubmed
Dai M, Al Odaini A, Fils Aimé N, Villatoro M, Guo J, Arakelian A, et al. Cyclin D1 cooperates with p21 to regulate TGF?-mediated breast cancer cell migration and tumor local invasion. Breast Cancer Res. 2013;15:R49 pubmed publisher
Newman R, Mobascher A, Mangold U, Koike C, Diah S, Schmidt M, et al. Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression. J Biol Chem. 2004;279:41504-11 pubmed
product information
Catalog Number :
11181
Product Name :
pcDNA cyclin D1 HA
article :
doi10.1074/jbc.M407349200
id459
pubmed_id15277517
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5400
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Please note that the cloning sites used for the cyclin D1 insert in this plasmid, EcoRI and XhoI, are not unique sites in this plasmid.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCL1, D11S287E, PRAD1, U21B31
geneCCND1
id595
genbank_ids
BC025302
mutation
namecyclin D1
shRNA_sequence
size1120
species
9606
Homo sapiens
tags
locationC terminal on insert
tagHA
resistance markers :
609
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA