This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
NFAT luciferase reporter
catalog :
10959
citations: 21
Reference
Nakamura M, Keller M, Fefelova N, Zhai P, Liu T, Tian Y, et al. Ser14 phosphorylation of Bcl-xL mediates compensatory cardiac hypertrophy in male mice. Nat Commun. 2023;14:5805 pubmed publisher
Harada N, Arahori Y, Okuyama M, Luis P, Joseph A, Kitakaze T, et al. Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid. Biochem Biophys Res Commun. 2022;595:41-46 pubmed publisher
Harada N, Okuyama M, Teraoka Y, Arahori Y, Shinmori Y, Horiuchi H, et al. Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin. NPJ Sci Food. 2022;6:4 pubmed publisher
Ajayi Smith A, van der Watt P, Mkwanazi N, Carden S, Trent J, Leaner V. Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells. Exp Cell Res. 2021;404:112637 pubmed publisher
Caron P, Broussaud S, Galano Frutos J, Sancho J, Savagner F. New variant (Val597Ile) in transmembrane region of the TSH receptor with human chorionic gonadotropin hypersensitivity in familial gestational hyperthyroidism. Clin Endocrinol (Oxf). 2020;: pubmed publisher
Messina A, Pulli K, Santini S, Acierno J, Känsäkoski J, Cassatella D, et al. Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism. Am J Hum Genet. 2019;: pubmed publisher
Gignac S, Hosseini Farahabadi S, Akazawa T, Schuck N, Fu K, Richman J. Robinow syndrome skeletal phenotypes caused by the WNT5AC83S variant are due to dominant interference with chondrogenesis. Hum Mol Genet. 2019;28:2395-2414 pubmed publisher
Carden S, van der Watt P, Chi A, Ajayi Smith A, Hadley K, Leaner V. A tight balance of Karyopherin β1 expression is required in cervical cancer cells. BMC Cancer. 2018;18:1123 pubmed publisher
Ahn S, Yang J, Kim N, Lee K, Cha Y, Yun J, et al. Anti-helminthic niclosamide inhibits Ras-driven oncogenic transformation via activation of GSK-3. Oncotarget. 2017;8:31856-31863 pubmed publisher
Durán J, Oyarce C, Pávez M, Valladares D, Basualto Alarcón C, Lagos D, et al. GSK-3?/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy. PLoS ONE. 2016;11:e0168255 pubmed publisher
Roy A, Dutta D, Iqbal J, Pisano G, Gjyshi O, Ansari M, et al. Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency. J Virol. 2016;90:8822-41 pubmed publisher
van der Watt P, Chi A, Stelma T, Stowell C, Strydom E, Carden S, et al. Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic. Mol Cancer Ther. 2016;15:560-73 pubmed publisher
Perez Neut M, Rao V, Gentile S. hERG1/Kv11.1 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurin-dependent mechanism. Oncotarget. 2016;7:58893-58902 pubmed publisher
Shaikh L, Zhou J, Teo A, Garg S, Neogi S, Figg N, et al. LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal. J Clin Endocrinol Metab. 2015;100:E836-44 pubmed publisher
Villanueva C, Jacobson Dickman E, Xu C, Manouvrier S, Dwyer A, Sykiotis G, et al. Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations. Genet Med. 2015;17:651-9 pubmed publisher
Osei Sarfo K, Gudas L. Retinoic acid suppresses the canonical Wnt signaling pathway in embryonic stem cells and activates the noncanonical Wnt signaling pathway. Stem Cells. 2014;32:2061-71 pubmed publisher
Greiner J, Müller J, Zeuner M, Hauser S, Seidel T, Klenke C, et al. 1,8-Cineol inhibits nuclear translocation of NF-?B p65 and NF-?B-dependent transcriptional activity. Biochim Biophys Acta. 2013;1833:2866-2878 pubmed publisher
Pont J, McArdle C, Lopez Bernal A. Oxytocin-stimulated NFAT transcriptional activation in human myometrial cells. Mol Endocrinol. 2012;26:1743-56 pubmed
Armstrong S, Caunt C, Fowkes R, Tsaneva Atanasova K, McArdle C. Pulsatile and sustained gonadotropin-releasing hormone (GnRH) receptor signaling: does the Ca2+/NFAT signaling pathway decode GnRH pulse frequency?. J Biol Chem. 2009;284:35746-57 pubmed publisher
Cowling B, McGrath M, Nguyen M, Cottle D, Kee A, Brown S, et al. Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy. J Cell Biol. 2008;183:1033-48 pubmed publisher
Ichida M, Finkel T. Ras regulates NFAT3 activity in cardiac myocytes. J Biol Chem. 2001;276:3524-30 pubmed
product information
Catalog Number :
10959
Product Name :
NFAT luciferase reporter
article :
doi10.1074/jbc.M004275200
id433
pubmed_id11044444
bacterial resistance :
Ampicillin
cloning :
backbonepGL2-Basic
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
A luciferase reporter containing three tandem repeats of a 30-bp fragment of the IL-2 promoter for analysis of NFAT activity. 30-bp fragment is GGAGG AAAAA CTGTT TCATA CAGAA GGCGT.
origin :
37
pi :
alt_names
IL-2
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5LucNRev
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIL-2, TCGF, lymphokine
geneIL2
id3558
genbank_ids
mutation
nameIL-2 promoter
shRNA_sequence
size90
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagluciferase
resistance markers :
146
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA