This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
siSlug3
catalog :
10905
citations: 8
Reference
Wang L, Hensch N, Bondra K, Sreenivas P, Zhao X, Chen J, et al. SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation. Cancer Res. 2021;81:5451-5463 pubmed publisher
Pomella S, Sreenivas P, Gryder B, Wang L, Milewski D, Cassandri M, et al. Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma. Nat Commun. 2021;12:192 pubmed publisher
Jury D, Daugaard I, Sanders K, Hansen L, Agalliu D, Pedersen I. miR-151a enhances Slug dependent angiogenesis. Oncotarget. 2020;11:2160-2171 pubmed publisher
Stern J, Hibshman G, Hu K, Ferrara S, Costello J, Kim W, et al. Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers. Mol Cancer Res. 2020;18:1050-1062 pubmed publisher
Hartel I, Ronellenfitsch M, Wanka C, Wolking S, Steinbach J, Rieger J. Activation of AMP-activated kinase modulates sensitivity of glioma cells against epidermal growth factor receptor inhibition. Int J Oncol. 2016;49:173-80 pubmed publisher
Zirkel A, Lederer M, Stöhr N, Pazaitis N, Huttelmaier S. IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG). Nucleic Acids Res. 2013;41:6618-36 pubmed publisher
Liu J, Uygur B, Zhang Z, Shao L, Romero D, Vary C, et al. Slug inhibits proliferation of human prostate cancer cells via downregulation of cyclin D1 expression. Prostate. 2010;70:1768-77 pubmed publisher
Gupta P, Kuperwasser C, Brunet J, Ramaswamy S, Kuo W, Gray J, et al. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005;37:1047-54 pubmed
product information
Catalog Number :
10905
Product Name :
siSlug3
article :
doi10.1038/ng1634
id414
pubmed_id16142232
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1
backbone_mutation
backbone_origin
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth notes :
Sequence: 5'-CAG ACC CAT TCT GAT GTA AAG-3'
origin :
37
pi :
alt_names
Slug siRNA
Slug
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5AgeI
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSLUG, SLUGH, SLUGH1, SNAIL2, WS2D
geneSNAI2
id6591
genbank_ids
mutation
namesiSlug
shRNA_sequence
size60
species
9606
Homo sapiens
tags
resistance markers :
568
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA