This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
siSlug2
catalog :
10904
citations: 6
Reference
Cutano V, Ferreira Mendes J, Escudeiro Lopes S, Machado S, Vinaixa Forner J, Gonzales Morena J, et al. LACTB exerts tumor suppressor properties in epithelial ovarian cancer through regulation of Slug. Life Sci Alliance. 2023;6: pubmed publisher
Wang L, Hensch N, Bondra K, Sreenivas P, Zhao X, Chen J, et al. SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation. Cancer Res. 2021;81:5451-5463 pubmed publisher
Pomella S, Sreenivas P, Gryder B, Wang L, Milewski D, Cassandri M, et al. Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma. Nat Commun. 2021;12:192 pubmed publisher
Wu J, Wu Y, Tung C, Tsai Y, Chen H, Chen Y, et al. DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression. Theranostics. 2020;10:8903-8923 pubmed publisher
Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher
Gupta P, Kuperwasser C, Brunet J, Ramaswamy S, Kuo W, Gray J, et al. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005;37:1047-54 pubmed
product information
Catalog Number :
10904
Product Name :
siSlug2
article :
doi10.1038/ng1634
id414
pubmed_id16142232
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1
backbone_mutation
backbone_origin
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth notes :
Sequence: 5'-GAG GAA AGA CTA CAG TCC AAG-3'
origin :
37
pi :
alt_names
Slug siRNA
Slug
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5AgeI
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSLUG, SLUGH, SLUGH1, SNAIL2, WS2D
geneSNAI2
id6591
genbank_ids
mutation
namesiSlug
shRNA_sequence
size60
species
9606
Homo sapiens
tags
resistance markers :
568
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA