This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBABE-puro TPR-Met
catalog :
10902
citations: 6
Reference
Antonica F, Santomaso L, Pernici D, Petrucci L, Aiello G, Cutarelli A, et al. A slow-cycling/quiescent cells subpopulation is involved in glioma invasiveness. Nat Commun. 2022;13:4767 pubmed publisher
Kitowska K, Gorska Arcisz M, Antoun D, Zarczynska I, Czaplinska D, Szczepaniak A, et al. MET-Pyk2 Axis Mediates Acquired Resistance to FGFR Inhibition in Cancer Cells. Front Oncol. 2021;11:633410 pubmed publisher
Bahcall M, Sim T, Paweletz C, Patel J, Alden R, Kuang Y, et al. Acquired METD1228V Mutation and Resistance to MET Inhibition in Lung Cancer. Cancer Discov. 2016;6:1334-1341 pubmed
Jahn S, LAW M, Corsino P, Davis B, Harrison J, Law B. Signaling mechanisms that suppress the cytostatic actions of rapamycin. PLoS ONE. 2014;9:e99927 pubmed publisher
Chan B, VanderLaan P, Sukhatme V. 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met. Biochem Biophys Res Commun. 2013;439:247-51 pubmed publisher
Gupta P, Kuperwasser C, Brunet J, Ramaswamy S, Kuo W, Gray J, et al. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet. 2005;37:1047-54 pubmed
product information
Catalog Number :
10902
Product Name :
pBABE-puro TPR-Met
article :
doi10.1038/ng1634
id414
pubmed_id16142232
bacterial resistance :
Ampicillin
cloning :
backbonepBABE-puro
backbone_mutation
backbone_origin
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
For a complete description of the TPR-met fusion, see PubMed ID: 3821733
origin :
37
pi :
alt_names
c-Met
TPR
MET
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3pBABE-3
sequencing_primer_5pBABE 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met
geneMET
id4233
aliasesMRT79
geneTPR
id7175
genbank_ids
mutationConstitutively active form of the c-Met receptor
nameTPR-Met
shRNA_sequence
size
species
9606
Homo sapiens
tags
plasmid copy :
G. Vande Woude
resistance markers :
568
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA