This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
809 pcDNA3 GFP PTEN
catalog :
10759
citations: 11
Reference
Zhang Y, Cao F, Zhou Y, Feng Z, Sit B, Krendel M, et al. Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes. Mol Biol Cell. 2019;30:622-635 pubmed publisher
Xu W, Li B, Zhao J, Yang J, Li J, Tsao S, et al. IGF2 induces CD133 expression in esophageal cancer cells to promote cancer stemness. Cancer Lett. 2018;425:88-100 pubmed publisher
Lin R, Xia S, Shan C, Chen D, Liu Y, Gao X, et al. The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells. Mol Cell. 2018;69:923-937.e8 pubmed publisher
Kimbrough Allah M, Millena A, Khan S. Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cells. Prostate. 2018;78:377-389 pubmed publisher
Riquelme S, Hopkins B, Wolfe A, Dimango E, Kitur K, Parsons R, et al. Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity. Immunity. 2017;47:1169-1181.e7 pubmed publisher
Malaney P, Palumbo E, Semidey Hurtado J, Hardee J, Stanford K, Kathiriya J, et al. PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. Cell Cycle. 2018;17:947-962 pubmed publisher
Li B, Xu W, Lam A, Wang Y, Hu H, Guan X, et al. Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy. Oncotarget. 2017;8:38755-38766 pubmed publisher
Qiu H, Li J, Clark L, Jackson A, Zhang L, Guo H, et al. JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer. Oncotarget. 2016;7:66809-66821 pubmed publisher
Yang S, Kim H. ROCK inhibition activates MCF-7 cells. PLoS ONE. 2014;9:e88489 pubmed publisher
Pattje W, Schuuring E, Mastik M, Slagter Menkema L, Schrijvers M, Alessi S, et al. The phosphatase and tensin homologue deleted on chromosome 10 mediates radiosensitivity in head and neck cancer. Br J Cancer. 2010;102:1778-85 pubmed publisher
Vazquez F, Grossman S, Takahashi Y, Rokas M, Nakamura N, Sellers W. Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex. J Biol Chem. 2001;276:48627-30 pubmed
product information
Catalog Number :
10759
Product Name :
809 pcDNA3 GFP PTEN
article :
doi10.1074/jbc.C100556200
id366
pubmed_id11707428
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5446
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta, TEP1
genePTEN
id5728
genbank_ids
mutation
namePTEN
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
locationN terminal on insert
tagGFP
resistance markers :
455
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA