This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
977 pSG5L HA PTEN A4
catalog :
10753
citations: 5
Reference
Wozniak D, Kajdacsy Balla A, Macias V, Ball Kell S, Zenner M, Bie W, et al. PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. Nat Commun. 2017;8:1508 pubmed publisher
Malaney P, Palumbo E, Semidey Hurtado J, Hardee J, Stanford K, Kathiriya J, et al. PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. Cell Cycle. 2018;17:947-962 pubmed publisher
van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher
Beckham T, Cheng J, Lu P, Marrison S, Norris J, Liu X. Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. PLoS ONE. 2013;8:e76593 pubmed publisher
Vazquez F, Ramaswamy S, Nakamura N, Sellers W. Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol. 2000;20:5010-8 pubmed
product information
Catalog Number :
10753
Product Name :
977 pSG5L HA PTEN A4
article :
doi10.1128/MCB.20.14.5010-5018.2000
id372
pubmed_id10866658
bacterial resistance :
Ampicillin
cloning :
backbonepSG5L-HA
backbone_mutation
backbone_origin
backbone_size4100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta, TEP1
genePTEN
id5728
genbank_ids
mutationA4: S380A, T382A, T383A, S385A
namePTEN
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
resistance markers :
455
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA