This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
800 pSG5L HA PTEN wt
catalog :
10750
citations: 18
Reference
Islam M, Xu Y, Tao W, Ubellacker J, Lim M, Aum D, et al. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018;2:850-864 pubmed publisher
Wozniak D, Kajdacsy Balla A, Macias V, Ball Kell S, Zenner M, Bie W, et al. PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. Nat Commun. 2017;8:1508 pubmed publisher
Malaney P, Palumbo E, Semidey Hurtado J, Hardee J, Stanford K, Kathiriya J, et al. PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer. Cell Cycle. 2018;17:947-962 pubmed publisher
Ahmed S, Macara I. The Par3 polarity protein is an exocyst receptor essential for mammary cell survival. Nat Commun. 2017;8:14867 pubmed publisher
González Sánchez A, Jaraíz Rodríguez M, Domínguez Prieto M, Herrero González S, Medina J, Tabernero A. Connexin43 recruits PTEN and Csk to inhibit c-Src activity in glioma cells and astrocytes. Oncotarget. 2016;7:49819-49833 pubmed publisher
Peng X, Giménez Cassina A, Petrus P, Conrad M, Rydén M, Arnér E. Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness. Sci Rep. 2016;6:28080 pubmed publisher
Li Y, Chandrasekaran V, Carter S, Woodward C, Christensen D, Dryden K, et al. Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids. elife. 2016;5: pubmed publisher
van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed publisher
Vallath S, Sage E, Kolluri K, Lourenco S, Teixeira V, Chimalapati S, et al. CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity. Sci Rep. 2016;6:24006 pubmed publisher
Horita H, Wysoczynski C, Walker L, Moulton K, Li M, Ostriker A, et al. Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation. Nat Commun. 2016;7:10830 pubmed publisher
Dhar S, Kumar A, Li K, Tzivion G, Levenson A. Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer. Biochim Biophys Acta. 2015;1853:265-75 pubmed publisher
Cui Y, Jiao H, Ye Y, Chen C, Wang J, Tang N, et al. FOXC2 promotes colorectal cancer metastasis by directly targeting MET. Oncogene. 2015;34:4379-90 pubmed publisher
Ohtake Y, Park D, Abdul Muneer P, Li H, Xu B, Sharma K, et al. The effect of systemic PTEN antagonist peptides on axon growth and functional recovery after spinal cord injury. Biomaterials. 2014;35:4610-26 pubmed publisher
Cordero Espinoza L, Hagen T. Increased concentrations of fructose 2,6-bisphosphate contribute to the Warburg effect in phosphatase and tensin homolog (PTEN)-deficient cells. J Biol Chem. 2013;288:36020-8 pubmed publisher
Beckham T, Cheng J, Lu P, Marrison S, Norris J, Liu X. Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. PLoS ONE. 2013;8:e76593 pubmed publisher
Bhoopathi P, Gorantla B, Sailaja G, Gondi C, Gujrati M, Klopfenstein J, et al. SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT. PLoS ONE. 2012;7:e36093 pubmed publisher
Cao J, Schulte J, Knight A, Leslie N, Zagozdzon A, Bronson R, et al. Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. EMBO J. 2009;28:1505-17 pubmed publisher
Ramaswamy S, Nakamura N, Vazquez F, Batt D, Perera S, Roberts T, et al. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci U S A. 1999;96:2110-5 pubmed
product information
Catalog Number :
10750
Product Name :
800 pSG5L HA PTEN wt
article :
doi10.1073/pnas.96.5.2110
id351
pubmed_id10051603
bacterial resistance :
Ampicillin
cloning :
backbonepSG5L-HA
backbone_mutation
backbone_origin
backbone_size4100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta, TEP1
genePTEN
id5728
genbank_ids
mutation
namePTEN
shRNA_sequence
size1200
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
resistance markers :
455
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA