This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGL3 2 kb prom. CD274
catalog :
107003
citations: 4
Reference
Madhi H, Lee J, Choi Y, Li Y, Kim M, Choi Y, et al. FOXM1 Inhibition Enhances the Therapeutic Outcome of Lung Cancer Immunotherapy by Modulating PD-L1 Expression and Cell Proliferation. Adv Sci (Weinh). 2022;9:e2202702 pubmed publisher
Deng Y, Xia X, Zhao Y, Zhao Z, Martínez C, Yin W, et al. Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance. Nat Commun. 2021;12:7041 pubmed publisher
Yan Y, Zheng L, Du Q, Yan B, Geller D. Interferon regulatory factor 1 (IRF-1) and IRF-2 regulate PD-L1 expression in hepatocellular carcinoma (HCC) cells. Cancer Immunol Immunother. 2020;: pubmed publisher
Coelho M, de Carné Trécesson S, Rana S, Zecchin D, Moore C, Molina Arcas M, et al. Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA. Immunity. 2017;47:1083-1099.e6 pubmed publisher
product information
Catalog Number :
107003
Product Name :
pGL3 2 kb prom. CD274
article :
doi10.1016/j.immuni.2017.11.016
id28192699
pubmed_id29246442
bacterial resistance :
Ampicillin
cloning :
backbonepGL3
backbone_mutation
backbone_originPromega
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth strain :
Modified Luciferase expression vector
origin :
37
pi :
alt_names
PD-L1, B7-H1
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5MluI
promoter
sequencing_primer_3TCTTTATGTTTTTGGCGTC
sequencing_primer_5 RVprimer3
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesB7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1
geneCD274
id29126
genbank_ids
mutation
nameCD274
shRNA_sequence
size2203
species
9606
Homo sapiens
tags
resistance markers :
1329
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA