This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pWZL Blast myc
catalog :
10674
citations: 19
Reference
Zimmerli D, Brambillasca C, Talens F, Bhin J, Linstra R, Romanens L, et al. MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling. Nat Commun. 2022;13:6579 pubmed publisher
Quintanal Villalonga Á, Taniguchi H, Zhan Y, Hasan M, Chavan S, Meng F, et al. Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation. J Hematol Oncol. 2021;14:170 pubmed publisher
Kuzuoğlu Öztürk D, Hu Z, Rama M, Devericks E, Weiss J, Chiang G, et al. Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Rep. 2021;35:109321 pubmed publisher
Shahrouzi P, Astobiza I, Cortázar A, Torrano V, Macchia A, Flores J, et al. Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis. Cancers (Basel). 2020;12: pubmed publisher
Li W, Hu J, Shi B, Palomba F, Digman M, Gratton E, et al. Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis. Nat Cell Biol. 2020;22:960-972 pubmed publisher
Murakami S, Nemazanyy I, White S, Chen H, Nguyen C, Graham G, et al. A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas. Dev Cell. 2019;51:113-128.e9 pubmed publisher
Yang Z, Shah K, Busby T, Giles K, Khodadadi Jamayran A, Li W, et al. Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer. J Clin Invest. 2018;128:3605-3618 pubmed publisher
Dang H, Takai A, Forgues M, Pomyen Y, Mou H, Xue W, et al. Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma. Cancer Cell. 2017;32:101-114.e8 pubmed publisher
Muranen T, Selfors L, Hwang J, Gallegos L, Coloff J, Thoreen C, et al. ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP. Cancer Res. 2016;76:7168-7180 pubmed
Hu B, Wang Q, Wang Y, Hua S, Sauvé C, Ong D, et al. Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth. Cell. 2016;167:1281-1295.e18 pubmed publisher
Avila A, Illing A, Becker F, Maerz L, Morita Y, Philipp M, et al. Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation. Nucleic Acids Res. 2016;44:6252-61 pubmed publisher
Sharma N, Magistroni V, Piazza R, Citterio S, Mezzatesta C, Khandelwal P, et al. BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene. Mol Cancer. 2015;14:132 pubmed publisher
Ben David E, Bester A, Shifman S, Kerem B. Transcriptional dynamics in colorectal carcinogenesis: new insights into the role of c-Myc and miR17 in benign to cancer transformation. Cancer Res. 2014;74:5532-40 pubmed publisher
Vander Griend D, Litvinov I, Isaacs J. Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation. Int J Biol Sci. 2014;10:627-42 pubmed publisher
Antony L, van der Schoor F, Dalrymple S, Isaacs J. Androgen receptor (AR) suppresses normal human prostate epithelial cell proliferation via AR/?-catenin/TCF-4 complex inhibition of c-MYC transcription. Prostate. 2014;74:1118-31 pubmed publisher
Gohar A, Cao R, Jenkins P, Li W, Houston J, Houston K. Subcellular localization-dependent changes in EGFP fluorescence lifetime measured by time-resolved flow cytometry. Biomed Opt Express. 2013;4:1390-400 pubmed publisher
Junk D, Cipriano R, Stampfer M, Jackson M. Constitutive CCND1/CDK2 activity substitutes for p53 loss, or MYC or oncogenic RAS expression in the transformation of human mammary epithelial cells. PLoS ONE. 2013;8:e53776 pubmed publisher
Magudia K, Lahoz A, Hall A. K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc. J Cell Biol. 2012;198:185-94 pubmed publisher
Boehm J, Hession M, Bulmer S, Hahn W. Transformation of human and murine fibroblasts without viral oncoproteins. Mol Cell Biol. 2005;25:6464-74 pubmed
product information
Catalog Number :
10674
Product Name :
pWZL Blast myc
article :
doi10.1128/MCB.25.15.6464-6474.2005
id361
pubmed_id16024784
bacterial resistance :
Ampicillin
cloning :
backbonepWZL Blast
backbone_mutation
backbone_origin
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
myc
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5pBABE 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesMRTL, MYCC, bHLHe39, c-Myc
geneMYC
id4609
genbank_ids
mutation
namec-myc
shRNA_sequence
size1700
species
9606
Homo sapiens
tags
resistance markers :
184
tags :
High Copy
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA