This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pMKO.1 puro p53 shRNA 2
catalog :
10672
citations: 13
Reference
Fuller A, Yang L, Hamilton A, Pirone J, Oldenburg A, Troester M. Epithelial p53 Status Modifies Stromal-Epithelial Interactions During Basal-Like Breast Carcinogenesis. J Mammary Gland Biol Neoplasia. 2021;: pubmed publisher
Oikawa T, Otsuka Y, Onodera Y, Horikawa M, Handa H, Hashimoto S, et al. Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity. Sci Rep. 2018;8:1595 pubmed publisher
Pan R, Ruvolo V, Mu H, Leverson J, Nichols G, Reed J, et al. Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy. Cancer Cell. 2017;32:748-760.e6 pubmed publisher
Luanpitpong S, Angsutararux P, Samart P, Chanthra N, Chanvorachote P, Issaragrisil S. Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma. Sci Rep. 2017;7:10607 pubmed publisher
Yang Z, Maciejowski J, de Lange T. Nuclear Envelope Rupture Is Enhanced by Loss of p53 or Rb. Mol Cancer Res. 2017;15:1579-1586 pubmed publisher
Van Roosbroeck K, Fanini F, Setoyama T, Ivan C, Rodriguez Aguayo C, Fuentes Mattei E, et al. Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers. Clin Cancer Res. 2017;23:2891-2904 pubmed publisher
Gómez V, Gundogdu R, Gomez M, Hoa L, Panchal N, O Driscoll M, et al. Regulation of DNA damage responses and cell cycle progression by hMOB2. Cell Signal. 2015;27:326-39 pubmed publisher
Kumar P P, Emechebe U, Smith R, Franklin S, Moore B, Yandell M, et al. Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. elife. 2014;3: pubmed publisher
Havel J, Li Z, Cheng D, Peng J, Fu H. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. Oncogene. 2015;34:1487-98 pubmed publisher
Tanabe K, Nakamura M, Narita M, Takahashi K, Yamanaka S. Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts. Proc Natl Acad Sci U S A. 2013;110:12172-9 pubmed publisher
Sandler V, Lailler N, Bouhassira E. Reprogramming of embryonic human fibroblasts into fetal hematopoietic progenitors by fusion with human fetal liver CD34+ cells. PLoS ONE. 2011;6:e18265 pubmed publisher
Gewinner C, Wang Z, Richardson A, Teruya Feldstein J, Etemadmoghadam D, Bowtell D, et al. Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Cancer Cell. 2009;16:115-25 pubmed publisher
Masutomi K, Yu E, Khurts S, Ben Porath I, Currier J, Metz G, et al. Telomerase maintains telomere structure in normal human cells. Cell. 2003;114:241-53 pubmed
product information
Catalog Number :
10672
Product Name :
pMKO.1 puro p53 shRNA 2
article :
doi10.1016/S0092-8674(03)00550-6
id362
pubmed_id12887925
bacterial resistance :
Ampicillin
cloning :
backbonepMKO.1
backbone_mutation
backbone_origin
backbone_size6700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
RNAi
growth notes :
Also reference: Stewart, S.A., Dykxhoorn, D.M., Palliser, D., Mizuno, H., Yu, E.Y., Eisen, H.N., Sabatini, D.M., Hahn, W.C., Sharp, P.A., Weinberg, R.A., et al. (2003). RNA 9, 493
origin :
37
pi :
alt_names
p53
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5AgeI
promoter
sequencing_primer_3pBABE-3
sequencing_primer_5pLXSN 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutation
namep53 shRNA
shRNA_sequenceGACTCCAGTGGTAATCTACT
size58
species
9606
Homo sapiens
tags
resistance markers :
184
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA