pMKO.1 puro p53 shRNA 1 | Addgene 10671 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pMKO.1 puro p53 shRNA 1

catalog :

10671

citations: 8

Reference
Kırımtay K, Selçuk E, Kelle D, Erman B, Karabay A. p53 regulates katanin-p60 promoter in HCT 116 cells. Gene. 2020;727:144241 pubmed publisher
Lin S, Yu L, Song X, Bi J, Jiang L, Wang Y, et al. Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response. Cell Death Dis. 2019;10:666 pubmed publisher
Arena G, Cissé M, Pyrdziak S, Chatre L, Riscal R, Fuentes M, et al. Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53. Mol Cell. 2018;69:594-609.e8 pubmed publisher
Ota A, Nakao H, Sawada Y, Karnan S, Wahiduzzaman M, Inoue T, et al. ?40p53? suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells. J Cell Sci. 2017;130:614-625 pubmed publisher
Ono T, Ota A, Ito K, Nakaoka T, Karnan S, Konishi H, et al. Plumbagin suppresses tumor cell growth in oral squamous cell carcinoma cell lines. Oral Dis. 2015;21:501-11 pubmed publisher
Liu L, Wang J, Shi L, Zhang W, Du X, Wang Z, et al. ?-Asarone induces senescence in colorectal cancer cells by inducing lamin B1 expression. Phytomedicine. 2013;20:512-20 pubmed publisher
Sandler V, Lailler N, Bouhassira E. Reprogramming of embryonic human fibroblasts into fetal hematopoietic progenitors by fusion with human fetal liver CD34+ cells. PLoS ONE. 2011;6:e18265 pubmed publisher
Masutomi K, Yu E, Khurts S, Ben Porath I, Currier J, Metz G, et al. Telomerase maintains telomere structure in normal human cells. Cell. 2003;114:241-53 pubmed

product information

Catalog Number :

10671

Product Name :

pMKO.1 puro p53 shRNA 1

article :

doi	10.1016/S0092-8674(03)00550-6
id	362
pubmed_id	12887925

bacterial resistance :

Ampicillin

cloning :

backbone

pMKO.1

backbone_mutation

backbone_origin

backbone_size

6700

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

Retroviral

RNAi

growth notes :

Also reference: Stewart, S.A., Dykxhoorn, D.M., Palliser, D., Mizuno, H., Yu, E.Y., Eisen, H.N., Sabatini, D.M., Hahn, W.C., Sharp, P.A., Weinberg, R.A., et al. (2003). RNA 9, 493 501. Note: There is no XhoI site in the shRNA oligo, as indicated on the author's map.

origin :

pi :

alt_names

p53

cloning

clone_method	Restriction Enzyme
cloning_site_3	EcoRI
cloning_site_5	AgeI
promoter
sequencing_primer_3	pBABE-3
sequencing_primer_5	pLXSN 5'
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	BCC7, BMFS5, LFS1, P53, TRP53
gene	TP53
id	7157

genbank_ids

mutation

name

p53 shRNA

shRNA_sequence

size

species

9606

Homo sapiens