This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFP Tubulin K40R
catalog :
105303
citations: 4
Reference
Villar Pazos S, Thomas L, Yang Y, Chen K, Lyles J, Deitch B, et al. Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy. Nat Commun. 2023;14:6547 pubmed publisher
Thomas G, Villar Pazos S, Thomas L, Yang Y, Chen K, Lyles J, et al. RNA-targeted therapy corrects neuronal deficits in PACS1 syndrome mice. Res Sq. 2023;: pubmed publisher
Kim J, Hwang H, Lee J, Kim M, Kim J. Cortactin deacetylation by HDAC6 and SIRT2 regulates neuronal migration and dendrite morphogenesis during cerebral cortex development. Mol Brain. 2020;13:105 pubmed publisher
Joo E, Yamada K. MYPT1 regulates contractility and microtubule acetylation to modulate integrin adhesions and matrix assembly. Nat Commun. 2014;5:3510 pubmed publisher
product information
Catalog Number :
105303
Product Name :
pEGFP Tubulin K40R
article :
doi10.1038/ncomms4510
id19822
pubmed_id24667306
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C1
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Original pEGFP-Tub from Clontech. Mutation in Tubulin was introduced by using site-directed mutagenesis kit (Stratagene)
growth strain :
To study effects of acetylation-null tubulin
origin :
37
pi :
alt_names
TUBA1B
cloning
clone_methodRestriction Enzyme
cloning_site_3Unknown
cloning_site_5Unknown
promoter
sequencing_primer_3
sequencing_primer_5CATGGTCCTGCTGGAGTTCGTG
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesK-ALPHA-1
geneTUBA1B
id10376
genbank_ids
NM_006082
mutationK40R
namealpha tubulin
shRNA_sequence
size1350
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagEGFP
resistance markers :
1793
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA