This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDH-SIRT2-Flag
catalog :
102624
citations: 3
Reference
Wang M, Zhang Y, Komaniecki G, Lu X, Cao J, Zhang M, et al. Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation. Nat Commun. 2022;13:4494 pubmed publisher
Chamberlain K, Huang N, Xie Y, LiCausi F, Li S, Li Y, et al. Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2. Neuron. 2021;109:3456-3472.e8 pubmed publisher
Jing H, Hu J, He B, Negrón Abril Y, Stupinski J, Weiser K, et al. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 2016;29:297-310 pubmed publisher
product information
Catalog Number :
102624
Product Name :
pCDH-SIRT2-Flag
article :
doi10.1016/j.ccell.2016.02.007
id28191961
pubmed_id26977881
bacterial resistance :
Ampicillin
cloning :
backbonepCDH-CMV-MCS-EF1-Puro
backbone_mutation
backbone_origin
backbone_size7384
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth strain :
Expresses full length SIRT2 isoform 1 in mammalian cells
origin :
37
pi :
alt_names
Sirtuin 2
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5EcoRI
promoterCMV
sequencing_primer_3CDH-Reverse, CTCTAGGCACCCGTTCAATTGC
sequencing_primer_5CMV-Forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSIR2, SIR2L, SIR2L2
geneSIRT2
id22933
genbank_ids
NC_000019.10
mutation
nameSIRT2
shRNA_sequence
size1215
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFlag
resistance markers :
3464
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA