This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV4a-SIRT2-Flag
catalog :
102623
citations: 3
Reference
Kim G, Bhattarai P, Lim S, Lee K, Choi H. Sirtuin 5-mediated deacetylation of TAZ at K54 promotes melanoma development. Cell Oncol (Dordr). 2023;: pubmed publisher
Yang J, Nicely N, Weiser B. Effects of Dimerization on the Deacylase Activities of Human SIRT2. Biochemistry. 2023;62:3383-3395 pubmed publisher
Jing H, Hu J, He B, Negrón Abril Y, Stupinski J, Weiser K, et al. A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. Cancer Cell. 2016;29:297-310 pubmed publisher
product information
Catalog Number :
102623
Product Name :
pCMV4a-SIRT2-Flag
article :
doi10.1016/j.ccell.2016.02.007
id28191961
pubmed_id26977881
bacterial resistance :
Kanamycin
cloning :
backbonepCMV-Tag-4A
backbone_mutation
backbone_origin
backbone_size4319
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses full length SIRT2 isoform 1 in mammalian cells
origin :
37
pi :
alt_names
Sirtuin 2
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5BamHI
promoterCMV
sequencing_primer_3T7 promoter
sequencing_primer_5T3 promoter
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSIR2, SIR2L, SIR2L2
geneSIRT2
id22933
genbank_ids
NC_000019.10
mutation
nameSirtuin 2
shRNA_sequence
size1182
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagFlag
resistance markers :
3464
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA