This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
IFN-Beta_pGL3
catalog :
102597
citations: 20
Reference
Caldwell S, Janosko C, Deiters A. Development of a light-activated STING agonist. Org Biomol Chem. 2024;22:302-308 pubmed publisher
Mo Y, Ye Y, Peng L, Sun X, Zhong X, Wu R. The central helicase domain holds the major conformational epitopes of melanoma differentiation-associated gene 5 autoantibodies. Rheumatology (Oxford). 2023;: pubmed publisher
Jiang B, Schmitt M, Rand U, Company C, Dramaretska Y, Grossmann M, et al. Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses. Sci Adv. 2023;9:eadf4975 pubmed publisher
Boudra R, Patenall B, King S, Wang D, Best S, Ko J, et al. PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma. bioRxiv. 2023;: pubmed publisher
Duncan Lowey J, Crabill E, Jarret A, Reed S, Roy C. The Coxiella burnetii effector EmcB is a deubiquitinase that inhibits RIG-I signaling. Proc Natl Acad Sci U S A. 2023;120:e2217602120 pubmed publisher
Du L, Liu W, Rosen S, Chen Y. Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression. J Mol Biol. 2023;435:167968 pubmed publisher
Zhu W, Wei L, Dong C, Wang Y, Kim J, Ma Y, et al. cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice. Mol Ther Nucleic Acids. 2022;30:421-437 pubmed publisher
Kim S, Choe M, Oh J, Kim J. Centrosome de-clustering of cancer cells induces cGAS-STING-mediated innate immunity of tumor-associated tumor cells in response to irradiation. Biochem Biophys Res Commun. 2022;636:24-30 pubmed publisher
Tabtieng T, Lent R, Kaku M, Monago Sanchez A, Gaglia M. Caspase-Mediated Regulation and Cellular Heterogeneity of the cGAS/STING Pathway in Kaposi's Sarcoma-Associated Herpesvirus Infection. MBio. 2022;13:e0244622 pubmed publisher
Yanase Y, Tsuji G, Nakamura M, Shibata N, Demizu Y. Control of STING Agonistic/Antagonistic Activity Using Amine-Skeleton-Based c-di-GMP Analogues. Int J Mol Sci. 2022;23: pubmed publisher
Taraphdar D, Singh B, Pattanayak S, Kiran A, Kokavalla P, Alam M, et al. Comodulation of Dengue and Chikungunya Virus Infection During a Coinfection Scenario in Human Cell Lines. Front Cell Infect Microbiol. 2022;12:821061 pubmed publisher
Xu Y, Chen K, Pan J, Lei Y, Zhang D, Fang L, et al. Repurposing clinically approved drugs for COVID-19 treatment targeting SARS-CoV-2 papain-like protease. Int J Biol Macromol. 2021;188:137-146 pubmed publisher
Vazquez C, Swanson S, Negatu S, Dittmar M, Miller J, Ramage H, et al. SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms. PLoS ONE. 2021;16:e0253089 pubmed publisher
Jansons J, Skrastina D, Kurlanda A, Petkov S, Avdoshina D, Kuzmenko Y, et al. Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer. Microorganisms. 2021;9: pubmed publisher
Jeremiah S, Miyakawa K, Matsunaga S, Nishi M, Kudoh A, Takaoka A, et al. Cleavage of TANK-Binding Kinase 1 by HIV-1 Protease Triggers Viral Innate Immune Evasion. Front Microbiol. 2021;12:643407 pubmed publisher
Mishra R, Banerjea A. SARS-CoV-2 Spike Targets USP33-IRF9 Axis via Exosomal miR-148a to Activate Human Microglia. Front Immunol. 2021;12:656700 pubmed publisher
Havranek K, White L, Bisom T, Lanchy J, Lodmell J. The Atypical Kinase RIOK3 Limits RVFV Propagation and Is Regulated by Alternative Splicing. Viruses. 2021;13: pubmed publisher
Wu J, Shi Y, Pan X, Wu S, Hou R, Zhang Y, et al. SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO. Cell Rep. 2021;:108761 pubmed publisher
Degen M, Girousi E, Feldmann J, Parisi L, La Scala G, Schnyder I, et al. A Novel Van der Woude Syndrome-Causing IRF6 Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes. Front Cell Dev Biol. 2020;8:583115 pubmed publisher
Gentili M, Kowal J, Tkach M, Satoh T, Lahaye X, Conrad C, et al. Transmission of innate immune signaling by packaging of cGAMP in viral particles. Science. 2015;349:1232-6 pubmed publisher
product information
Catalog Number :
102597
Product Name :
IFN-Beta_pGL3
article :
doi10.1126/science.aab3628
id28191948
pubmed_id26229115
bacterial resistance :
Ampicillin
cloning :
backbonepGL3
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth strain :
IFN-beta promoter driving luciferase. Use in IFN reporter assay.
origin :
30
pi :
alt_names
cloning
clone_methodUnknown
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5unknown
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIFB, IFF, IFN-beta, IFNB
geneIFNB1
id3456
genbank_ids
mutation
nameHuman IFN-Beta promoter
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagluciferase
resistance markers :
3219
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA