pcDNA3.1-hNurr1-NE | Addgene 102363 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pcDNA3.1-hNurr1-NE

catalog :

102363

citations: 7

Reference
Stiller T, Merk D. Exploring Fatty Acid Mimetics as NR4A Ligands. J Med Chem. 2023;66:15362-15369 pubmed publisher
Sai M, Vietor J, Kornmayer M, Egner M, L xf3 pez Garc xed a x, H xf6 fner G, et al. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J Med Chem. 2023;66:13556-13567 pubmed publisher
Ballarotto M, Willems S, Stiller T, Nawa F, Marschner J, Grisoni F, et al. De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023;66:8170-8177 pubmed publisher
Vietor J, Gege C, Stiller T, Busch R, Schallmayer E, Kohlhof H, et al. Development of a Potent Nurr1 Agonist Tool for In Vivo Applications. J Med Chem. 2023;66:6391-6402 pubmed publisher
Willems S, Marschner J, Kilu W, Faudone G, Busch R, Duensing Kropp S, et al. Nurr1 Modulation Mediates Neuroprotective Effects of Statins. Adv Sci (Weinh). 2022;9:e2104640 pubmed publisher
Willems S, Müller M, Ohrndorf J, Heering J, Proschak E, Merk D. Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries. ChemMedChem. 2022;17:e202200026 pubmed publisher
Wan P, Leung T, Siu M, Mo X, Tang H, Chan K, et al. HPV-induced Nurr1 promotes cancer aggressiveness, self-renewal, and radioresistance via ERK and AKT signaling in cervical cancer. Cancer Lett. 2021;497:14-27 pubmed publisher

product information

Catalog Number :

102363

Product Name :

pcDNA3.1-hNurr1-NE

article :

doi
id	28191886
pubmed_id

bacterial resistance :

Ampicillin

cloning :

backbone

pcDNA3.1(+)

backbone_mutation

backbone_origin

Invitrogen

backbone_size

5900

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

This plasmid encodes a novel 18-amino-acid protein tag - NE , which can be detected by a specific mouse monoclonal antibody in Western blotting, immunopreciptation, and immunocytochemistry. (Source of antibody: http://www.versitech.hku.hk/reagents/ne/)

growth strain :

Overexpression of NR4A2 nuclear receptor subfamily 4 group A member 2 in mammalian cells

origin :

pi :

alt_names

Nurr1

NOT; RNR1; HZF-3; TINUR

cloning

clone_method	Restriction Enzyme
cloning_site_3	BamHI
cloning_site_5	HindIII
promoter	CMV
sequencing_primer_3	BGH-R
sequencing_primer_5	T7 primer/CMV-F primer
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	HZF-3, IDLDP, NOT, NURR1, RNR1, TINUR
gene	NR4A2
id	4929

genbank_ids

mutation

name

NR4A2 nuclear receptor subfamily 4 group A member 2

shRNA_sequence

size

1851

species

9606

Homo sapiens