This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCXN2-HA-AT1R-YFP
catalog :
101659
citations: 6
Reference
Martínez V, Martins Lima A, Stergiopulos N, Velez Rueda J, Islas M, Griera M, et al. Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy. Eur J Pharmacol. 2023;946:175654 pubmed publisher
Sauge E, Pechkovsky D, Atmuri N, Tehrani A, White Z, Dong Y, et al. Losartan metabolite EXP3179 is a unique blood pressure-lowering AT1R antagonist with direct, rapid endothelium-dependent vasoactive properties. Vascul Pharmacol. 2022;147:107112 pubmed publisher
Yeung M, Teng J, Jia L, Zhang C, Huang C, Cai J, et al. Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021;184:2212-2228.e12 pubmed publisher
Volonte D, Sedorovitz M, Cespedes V, Beecher M, Galbiati F. Cell autonomous angiotensin II signaling controls the pleiotropic functions of oncogenic K-Ras. J Biol Chem. 2021;296:100242 pubmed publisher
Burr M, Sparbier C, Chan K, Chan Y, Kersbergen A, Lam E, et al. An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer. Cancer Cell. 2019;36:385-401.e8 pubmed publisher
Inuzuka T, Fujioka Y, Tsuda M, Fujioka M, Satoh A, Horiuchi K, et al. Attenuation of ligand-induced activation of angiotensin II type 1 receptor signaling by the type 2 receptor via protein kinase C. Sci Rep. 2016;6:21613 pubmed publisher
product information
Catalog Number :
101659
Product Name :
pCXN2-HA-AT1R-YFP
article :
doi10.1038/srep21613
id28191752
pubmed_id26857745
bacterial resistance :
Ampicillin
cloning :
backbonepCXN2
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Expresses AT1R with HA tag and YFP in mammalian cells.
growth temp :
DH5alpha is also a suitable growth strain.
origin :
37
pi :
alt_names
AT1R
AGTR1
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5EcoRI (with HA)
promoterCAG promoter
sequencing_primer_3unknown
sequencing_primer_5unknown
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R
geneAGTR1
id185
genbank_ids
NM_000685.4
mutation
nameAngiotensin II type 1 receptor
shRNA_sequence
size1114
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHA
locationC terminal on backbone
tagYFP (Venus)
resistance markers :
3637
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA