Uhrf1 antibody (mAb) | Active Motif 61341 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

Uhrf1 antibody (mAb)

catalog :

61341

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1RC-1C10

reactivity :

human, mouse, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation, immunohistochemistry knockout validation

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 1f western blot knockout validation; mouse; 1:1000; loading ...; fig 1e immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1a	Pan H, Jiang N, Sun S, Jiang H, Xu J, Jiang X, et al. UHRF1-repressed 5'-hydroxymethylcytosine is essential for the male meiotic prophase I. Cell Death Dis. 2020;11:142 pubmed publisher
immunohistochemistry - paraffin section; pigs ; 1:300; loading ...; fig 1i	Kobayashi T, Zhang H, Tang W, Irie N, Withey S, Klisch D, et al. Principles of early human development and germ cell program from conserved model systems. Nature. 2017;546:416-420 pubmed publisher

product information

Catalog Number :

61341

Product Name :

Uhrf1 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

1RC-1C10

Isotype :

IgG1k

CrossReactivity :

Human

Background :

Uhrf1 (ubiquitin-like, containing PHD and RING finger domains 1) is a transcription and cell cycle regulator. It functions as a putative E3 ubiquitin-protein ligase. Uhrf1 is important for G1/S transition of the cell cycle. It is also believed that Uhrf1 may help recruit the DNA methyltransferase, DNMT1, to hemimethylated DNA and assist in the stabilization of DNMT1 with chromatin.

Immunogen :

This antibody was raised against a synthetic peptide corresponding to amino acid residue(s) 263-793 of human Uhrf1.

Uses :

IF, IHC, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: The use of this antibody is described in the following References:WB & IP: Felle, M. et al. (2011) Nucleic Acids Res. 39:8355-8365.WB, IF & IHC: Hopfner, R. et al. (2000) Cancer Res. 60:121-128.