HIF-1 alpha antibody (mAb) | Active Motif 61275 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

HIF-1 alpha antibody (mAb)

catalog :

61275

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ESEE122

The same clone is also sold as:

QED Bioscience: 34039
OriGene: TA309690, TA326476
Invitrogen: MA5-16019, MA5-16018, MA5-45252, MA5-16020, MA1-16518, 14-9100-82, MA5-45251, MA5-16016, MA5-45250, MA5-16017, 14-9100-80
Novus Biologicals: NBP2-80762, NB100-131
StressMarq Biosciences: SMC-184
Abcam: ab8366
Rockland Immunochemicals: 200-301-F45
Abnova: MAB2342

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 4	Edalat L, Stegen B, Klumpp L, Haehl E, Schilbach K, Lukowski R, et al. BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget. 2016;7:14259-78 pubmed publisher

product information

Catalog Number :

61275

Product Name :

HIF-1 alpha antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

ESEE122

Isotype :

IgG1

CrossReactivity :

Bovine, Human, Mouse, Rat

Background :

HIF-1 (hypoxia inducible factor 1, alpha subunit, MOP1, PASD8, bHLHe78, PAS domain-containing protein 8) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.

Immunogen :

This HIF-1 alpha antibody was raised against a partial protein containing amino acid residues 329-530 of human HIF-1 alpha.

Uses :

IHC

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: The use of this antibody is described in the following references:IHC: Yoshimura H et al. (2004) Clinical Cancer Res 10:8554-8560.Tan E.Y. et al. (2007) Breast Cancer Res 9(6):R89.Beasley N.J.P. (2008) Cancer Res 62:2493-2497.