PRDM1 / BLIMP1 antibody (mAb) | Active Motif 61167 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

PRDM1 / BLIMP1 antibody (mAb)

catalog :

61167

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ROS195

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, FACS

product information

Catalog Number :

61167

Product Name :

PRDM1 / BLIMP1 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

ROS195

Isotype :

IgG1

CrossReactivity :

Human

Background :

PRDM1 / BLIMP1 is a transcriptional repressor that binds to specific target sites in DNA and recruits co-repressors. PRDM1 / BLIMP1 is a master regulator for B cell terminal differentiation, is essential for normal development and immunity and a putative tumor suppressor in diffuse large B cell lymphomas (DLBCLs). PRDM1 / BLIMP1 specifies primordial germ cells through the silencing of the default somatic pathway. PRDM1 / BLIMP1 also acts as a master regulator of intestinal maturation.

Immunogen :

This PRDM1 / BLIMP1 antibody was raised against full-length recombinant human PRDM1 / BLIMP1 protein.

Uses :

FACS, IHC, IP, WB

Storage :

Antibodies in solution can be stored at -20M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Product References :

References: This antibody has been used in the following references: IHC: Garcia JF et al. (2006) Haematologica 91: 467 - 474 ; Nie K et al. (2008) Am J Pathol 173: 242 - 252; Liu YY et al. (2007) Blood 173: 242 - 252; Zhao WL et al. (2008) Blood 111: 3867 - 3871.WB: Garcia JF et al. (2006) Haematologica 91: 467 - 474 ; Nie K et al. (2008) Am J Pathol 173: 242 - 252; Liu YY et al. (2007) Blood 173: 242 - 252; Zhao WL et al. (2008) Blood 111: 3867 - 3871.