PIM2 antibody (mAb) | Active Motif 61159 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

PIM2 antibody (mAb)

catalog :

61159

quantity :

100 ug

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

CHU61

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:3000; fig 2	Kreuz S, Holmes K, Tooze R, Lefevre P. Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. Mol Cancer. 2015;14:205 pubmed publisher

product information

Catalog Number :

61159

Product Name :

PIM2 antibody (mAb)

Host Species :

Rat

Clonality :

Monoclonal

Size :

100 ug

Clone :

CHU61

Isotype :

IgG2a

CrossReactivity :

Human

Background :

PIM2 is a serine/threonine protein kinase in the CAMK family. PIM2 promotes cell survival in response to a variety of proliferative signals through activation of the I-M-NM-:B kinase/NF-M-NM-:B pathway. It also inhibits apoptosis through the phosphorylation of BAD. PIM2 has been implicated in the transformation of both T and B lymphocytes and is highly expressed in human leukemia and lymphomas, as well as adenocarcinomas and hepatocellular carcinomas.

Immunogen :

This PIM2 antibody was raised against a recombinant protein corresponding to human PIM2.

Uses :

IHC, IP, WB

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.