DAP-5 antibody (mAb) | Active Motif 40964 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Active Motif

other brands :

Geneka Biotechnology

product type :

antibody

product name :

DAP-5 antibody (mAb)

catalog :

40964

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

39C534

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

40964

Product Name :

DAP-5 antibody (mAb)

Host Species :

Mouse

Clonality :

Monoclonal

Size :

100 ug

Clone :

39C534

Isotype :

IgG1

CrossReactivity :

Human, Mouse

Background :

DAP-5 (eIF4G2 or eukaryotic translation initiation factor 4 gamma 2) shares similarity with the C-terminal region of eIF4G, which contains the binding sites for eIF4A and eIF3. eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. DAP-5 appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection.

Immunogen :

This antibody was raised against a synthetic peptide corresponding to amino acid residues 796-812 of human DAP-5.

Uses :

Storage :

Antibodies in solution can be stored at -80M-BM-0C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.